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Biomedical subjects

V Pellissier

Publications and source records attributed to V Pellissier.

5 recordsLinked to original sources
PubMed2002

[Mandatory disclosure and infectious disease. From "pestilential" disease to "emerging" diseases].

Due to the recent overhaul of the procedure on mandatory disclosure of infectious diseases (law relating to the reinforcement of sanitation quality control established in July 1998, and the May 1999 and May 2001 decrees on the application of this law), wishing to take advantage of this opportunity, the authors propose a chronological review retracing the history of these legal declarations. For over a century, they have represented the main instrument used for intervention and surveillance allowing for the fight against infectious diseases. The health options kept have varied over the years, as well as the precautions taken to respect secrecy (nominative or anonymous disclosure, modalities of transmission...). Procedures adopted to reconcile the principle of confidentiality along with the necessity to protect public health in the case where it would require an immediate and urgent intervention are examined throughout the chronology (determining the source of contamination, prevention of contagion).

Communicable Diseases, Emerging↗
PubMed2000

Clinical evaluation of heparin-coated circuits for routine coronary artery bypass grafting surgery: a prospective randomized study.

The aim of this study was to demonstrate the clinical and biological benefits of heparin-coated circuits in routine coronary artery bypass grafting (CABG). A prospective, randomized study was conducted in 80 patients undergoing routine CABG. Patients were randomized to either noncoated circuits (Group 1) or heparin-coated circuits (Group 2). A complete clinical evaluation was performed preoperatively at Days 0, 1, 2, and 3 and at discharge day and combined with extensive laboratory tests for hemostasis and inflammatory response. This study did not prove any major statistically significant clinical benefit of heparin-coated circuits in low risk patients. Postoperative bleeding, significantly less in the heparin-coated group, did not decrease significantly the number of transfused patients. Biological values were not changed significantly except for factor II and monocytes, which were higher in Group 2. Heparin-coated circuits offer minimal clinical and biological benefits for routine CABG surgery. However, they may prove beneficial for complex procedures or at-risk patients.

Aged↗
PubMedDate not supplied

[Research using the human embryo. A timely question].

There has been a considerable amount of debate in Europe on the use of the human embryo in research, a key point in the ongoing examination of bioethics laws. The French Academy of Medicine, the National Consultative Committee on Ethics, the State Council and the Parliamentary Office for the evaluation of scientific and technologic decisions have all made formal statements. An examination of these opinions discloses that there is a critical agreement concerning the Laws of July 1994 and on the requirement for a better text regulating research on the human embryo. It is becoming very clear that an international harmonization will probably not be possible on this point. In this context, where research on the human embryo is authorized in the United States, it is reasonable to expect fundamental discoveries which will be of fundamental importance for all scientific disciplines, emphasizing the need for further thought on our protectionist legal position.

Embryo, Mammalian↗