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Biomedical subjects

V Pishkin

Publications and source records attributed to V Pishkin.

At least 19 recordsLinked to original sources
PubMed1992

Systolic blood pressure and neuropsychological test performance of alcoholics.

This study examined resting systolic blood pressure (SBP) as a mediator of neuropsychological (NP) test performance in nonhypertensive alcoholics and controls. A median-split was used to assign alcoholics and controls to low and high SBP groups. Results showed that: (1) When SBP level was not considered, alcoholics only performed worse than controls on the WAIS Comprehension subtest. (2) Alcoholics and controls in the high SBP groups had fewer correct items on the WAIS Comprehension and Raven's, Set I tests than subjects in the low SBP groups. (3) Significant Diagnostic Group by SBP Group interaction was found for the Sentence Writing test. For this test only controls in the High SBP Group did worse than controls in the Low SBP Group. (4) Individual group comparisons for all NP tests showed that alcoholics in the High SBP Group were more impaired than controls in the Low SBP Group on the WAIS Comprehension, Shipley Abstraction Age and Stark Visual-Spatial tests; but alcoholics in the Low SBP Group did not differ from, or outperformed, controls in the High SBP Group on the WAIS Comprehension, Shipley Abstraction Age, Raven's, Set I, and Stark Visual-Spatial tests. These data demonstrate that both alcoholism and high SBP adversely and differentially affect the NP test performance of alcoholics and controls.

Adult↗
PubMed1992

Resting cardiovascular activity and antisocial behavior in Essential and Reactive alcoholic men.

This study showed that 10 men identified as Essential alcoholics had significantly lower resting systolic and diastolic blood pressures and significantly higher scores on Latcham's measure of antisocial behavior than 11 Reactive alcoholics. For all alcoholics the antisocial measure was positively correlated with the total score on the Rudie-McGaughran questionnaire. Also, the antisocial measure was negatively correlated with diastolic blood pressure and heart rate. If lower resting cardiovascular activity were a psychophysiological indicator of more antisocial behavior, change on both variables could be associated with initiation and maintenance of alcoholic drinking by Essential alcoholic men.

Adult↗
PubMed1992

Factor analysis of the Rudie-McGaughran Essential-Reactive questionnaire for VA alcoholic men.

In this study factor analysis was used to estimate the validity of the Rudie-McGaughran Essential-Reactive questionnaire. Answers of VA alcoholic men were tape-recorded and scored using the Rudie and McGaughran criteria. Only 2 factors, economic dependence and gastrointestinal symptoms, were validated using factor analysis. Five of the remaining six factors evaluated dimensions of dependence unique to the Essential alcoholic men.

Activities of Daily Living↗
PubMed1991

Psychophysiological activity and neuropsychological test performance in alcoholics.

This study examined electromyogram (EMG) and skin conductance level (SCL) as mediators of neuropsychological test performance of alcoholics. Alcoholics and controls with high EMG performed less well than low EMG subjects on 12 measures of neuropsychological performance. For SCL, the alcoholics and controls in the Low Group did not differ from those in the High Group on any measure. Analyses that used information intake (Low EMG and High SCL) and rejection (High EMG and Low SCL) information postures (IPs) demonstrated that the intake group outperformed the rejection group on 10 neuropsychological measures. Subjects with intake IPs reported more stimulation, concentration, and interest during the tasks than did subjects with rejection IPs. Results suggest that IPs can be used to identify alcoholics with neuropsychological deficits.

Alcoholism↗
PubMed1991

Differences between essential and reactive alcoholics on tests of neuropsychological functioning and affect.

This study tested the hypothesis that Essential Alcoholics (n = 15) develop a more severe form of alcoholism than Reactive Alcoholics (n = 12). VA alcoholic patients were classified as Essential or Reactive Alcoholics, using the Rudie-McGaughran questionnaire, and tested on four neuropsychological tests, the Neuropsychological Impairment Scale, the Beck Depression Inventory, Tarter's Hyperactivity/Minimal Brain Dysfunction questionnaire, and Latcham's Measure of Antisocial Behavior. While the two groups did not differ in age, education, or Family History of alcoholism. Essential Alcoholics had an earlier age of onset and a longer chronicity of alcoholism. After analysis of covariance was used to control for group differences in age of onset and chronicity, Essential Alcoholics were still significantly higher on depression and significantly more impaired on five subtests of the Neuropsychological Impairment Scale: global measure, total items, general, learning-verbal, and frustration. Nonsignificant group differences, in the expected direction, were found for the Shipley Mental Age and Tarter's questionnaire. These results suggest that Essential Alcoholics have higher depression scores and greater impairments in neuropsychological functioning than Reactive Alcoholics.

Adult↗
PubMed1987

Physiological responses of type A and type B men during cognitive performance.

Twenty male medical students classified as Type A or Type B solved a Concept Identification (CI) problem while measurements were taken on cardiovascular and somatic activity. The As produced significantly more overall electromyogram (EMG) activity and greater vasomotor activity than the Bs at baseline and during the task. Both Type As and Bs showed significantly higher levels of Heart Rate (HR), systolic and diastolic blood pressures, skin conductance, frontal EMG, and lower levels of vasomotor activity during work on the problem than during pre- and post-problem baselines. Type As showed significant negative correlations between total errors during CI and level of vasomotor activity, and between postsolution response latency and skin conductance. Type Bs showed a strong positive association between presolution response time and heart rate that did not hold for the As. The As appear to have shown sympathetic activation associated with quality of problem-solving performance, while the B's showed a relationship that suggested an impaired efficiency of performance associated with cardiac activation.

Adult↗
PubMed1986

Thought disorder and schizophrenia: isolating and timing a mental event.

This study explored the ability of nonparanoid schizophrenic, paranoid schizophrenic, and mixed psychiatric control (manics and schizoaffectives) patients to perform on two types of conceptual, speeded inference (SI) tasks, which differ in type of abstraction process required. The subjects (N = 30) were grouped into high and low levels of thought dysfunction, as measured by the Whitaker Index of Schizophrenic Thinking (WIST). There were no differences among the three clinical groups on the conceptual, SI tasks. Reaction times differed reliably across the two SI tasks. High-WIST subjects were impaired on SI accuracy. Significant impairment in accuracy was demonstrated by high-WIST time and error groups on the more complex SI tasks. Information processing deficit was demonstrated in terms of encoding phase and reaction time in problem-solving of the three diagnostic groups as a function of WIST levels.

Adult↗
PubMed1979

Randomness and the "streaking" phenomenon: attentional anomalies in performance on the Whitaker Index of Schizophrenic Thinking (WIST).

Examined in detail the performance of 36 hospitalized male schizophrenics on the Whitaker Index of Schizophrenic Thinking (WIST). Results indicated two interesting phenomena. First, the performance of patients with the highest level of cognitive deficit approached a random level of responding with respect to both the type of error made and the propensity to improve after an error. Second, a subgroup of these highly impaired Ss, identified as "streakers," displayed periods of virtually error-free responding, interspersed with periods of extremely impaired performance. The streaking phenomenon, as well as the tendency toward randomness, was discussed in terms of attentional anomalies.

Adult↗
PubMed1978

Factored scales for the Personal Health Survey with schizophrenics, alcoholics, felons, unmarried mothers, and college students.

Employed the Personal Health Survey (PHS) to study patterns of symptomology related to physical and mental health in a population of 730 Ss, which consisted of five subgroups: felons, hospitalized alcoholics, unmarried mothers, college students and institutionalized schizophrenics. The factorial data were analyzed in terms of (a) size of item factor loadings; (b) base rates of responding True to each item; and (c) clinical judgments as to the specificity and meaning of the items and factor scale patterns. Five main factors were extracted: Factor I--General health status; Factor II--Sociopathic character disorders; Factor III--Mixed psychiatric symptoms; Factor IV--Anxiety state with psychosomatic symptoms and general nervousness; and Factor V--Schizophrenicity.

Alcoholism↗
PubMed1978

The factorial structure of the Personal Health Survey in normals and schizophrenics.

Administered the Personal Health Survey to five different groups: 74 incarcerated felons, 47 hospitalized alcoholics, 172 unmarried mothers, 51 college students, and 386 hospitalized chronic schizophrenics. On 191 of 200 items, the schizophrenics had higher base rates than any other group. Although some groups did not have large enough Ns for statistically adequate factor analyses, factorial studies also were done on the four control groups. Every group studied gave different factor patterns, with different orders of emergence of factors, different item loadings and heterogeneous composition of items. It is concluded that subgroups should be factored independently across time to determine population characteristics because overall population patterns do not make possible more than general predictions about subgroups. Individuals cannot be predicted from either overall or subgroup factorial characteristics.

Affective Symptoms↗
PubMed1977

A factorial structure of the dimensions of femininity in alcoholic, schizophrenic and normal populations .

The Femininity Study was administered tl 31 alcoholic females, 146 college females, and 152 female schizophrenic patients. The data were factor analyzed: five major factors were identified: (1) heterosexual social role inadaptability; (2) parental role inadaptability; (3) homemaker role inadaptability; (4) general affective (neurotic) instability; and (5) maternal role inadaptability. The institutionalized women showed much greater incidence of all types of inadaptability.

Adult↗
PubMed1977

Relationship between schizophrenic thinking and MMPI for process and reactive patients.

This study examined the relationship between Whitaker Index of Schizophrenic Thinking (WIST) and MMPI performance in 25 male Process and Reactive schizophrenic inpatients. The results demonstrated a correlation between the WIST index and the Sc scale of the MMPI (r = .54, p less than .05) for Process patients only. Other MMPI scales highly correlated with each other also correlated with WIST index for the Process group. The lack of association between WIST and MMPI scales for Reactive patients was interpreted as suggesting a high degree of behavioral disorganization in these patients. Other results, i.e., lack of correlation between time and error scores on the WIST and high variability of time scores on the WIST, suggest that part of this disorganization for the Reactive patients may be understood in terms of disrupted pacing of behavior with respect to time, a process that may be related to the intrusion of irrelevant event processing.

Adult↗
PubMed1977

Comparative study of the factorial composition of femininity in alcoholic, schizophrenic and normal populations.

The Femininity Study (Thorne, 1965) was administered to a total of 329 women, which included alcoholic females, Skidmore College students, University of Alberta students, and institutionalized chronic undifferentiated schizophrenics. In the alcoholic women, the first five factors were labeled high interpersonal adaptability, heterosexual role inadaptability, female role ambivalence, female identification problems, and maternal role inadaptability. In the Skidmore College population, the first five factors were heterosexual role inadaptability, general female role inadaptability, physical and/or psychosomatic disabilities with low female self-concepts, positive female self-concepts and interests, and emancipated female role concepts. In the University of Alberta women, the first five factors were heterosexual and general social inadaptability, heterosexual interests and adaptability, homosexual tendencies, conflictual sexuality, and emancipated female role concepts. In the institutionalized schizophrenics, the five factors were homosexual conflicts, heterosexual adaptability, rejection of parental-caretaker roles, promiscuity, and negative sexual self-concepts.

Alcoholism↗
PubMed1977

Schizophrenic cognitive dysfunction: a deficit in rule transfer.

This study examined conceptual rule learning (RL) deficit in male schizophrenic Ss categorized into three groups as defined by Whitaker Index of Schizophrenic Thinking (WIST). Ss were administered a conjunctive, disjunctive, conditional or biconditional rule learning task, WIST, and Shipley-Hartford Memory Scale. It was shown that: (a) the WIST reliably differentiates among three levels of thought disorder as reflected by a deficit in inter-problem transfer of rule learning; (b) certain WIST and Shipley parameters reliably predict RL performance; and (c) phenothiazine dosage levels show no influence on the WIST and no correlation with RL. The findings indicate that cognitive dysfunction in schizophrenics is evidenced by limited inductive reasoning, insufficient channel capacity for filtering out irrelevant information, and inability to gain from antecedent RL experience. Principal locus of schizophrenic thought disorder is examined within a stimulus encoding-information processing paradigm.

Adult↗
PubMed1977

A factorial study of personal development of unmarried mothers, college, alcoholic, and schizophrenic populations.

Reported the results of a factor analytic study of the Personal Development Study (PDS). The PDS was administered for research purposes to four diagnostic groups, which included 89 institutionalized alcoholics, 336 unmarried mothers, 159 college students, and 388 chronic schizophrenics. A principal component factor analysis with Varimax rotation performed on the combined populations (N = 972) yielded five main factors labeled as projection, optimism-responsibility, reaction and symptom formation, repressive-compulsive, and intropunitiveness-guilt. Analysis of base rates of responding to the individual items revealed that the four populations ranged along a continuum, with the normals at one extreme and the institutionalized schizophrenics at the other extreme of greater pathological responding.

Adolescent↗
PubMed1977

The factorial structure of personal development mechanisms in unmarried mothers, college, alcoholic, and schizophrenic populations.

The Personal Development Study (PDS) was administered to four diagnostic groups, which included 89 hospitalized alcoholics, 336 unmarried mothers, 159 college students, and 387 chronic institutionalized schizophrenics. The PDS data from the four groups were factor analyzed separately by Varimax rotation of principal component factors. Cluster analysis methods were used to compare the separate diagnostic group factors with the overall factors previously reported by Pishkin and Thorne (1977). Only a few close fits of the diagnostic group factors showed large differences in item composition, order of emergence of factors and size of loadings between groups. Because many items and factors could be interpreted in terms of several alternative theoretical systems, interpretations were based on the clinical meanings of items and clusters in terms of integration theory (Thorne, 1976).

Adolescent↗
PubMed1977

Cognitive rigidity in information processing of chronic undifferentiated schizophrenics.

This study investigated Concept Identification (CI) performance and hypothesis behavior of 100 chronic undifferentiated schizophrenic and matched normal Ss as functions of motor-cognitive, personality-perceptual, and psychomotor speed parameters of rigidity. The CI task was designed to test the effects of five levels of information complexity and to examine 10 categories of hypothesis strategies utilized in conceptual problem solving. It was found that normals were superior to schizophrenics in CI and that schizophrenics performed more poorly than normals at higher complexity levels. Normals were markedly less rigid on the motor-cognitive dimension than were schizophrenics. Correlational analysis revealed a number of reliable relationships between the three rigidity measures and the 10 hypothesis categories. Some insight was gained about the role of rigidity in utilization of effective strategies in problem solving; the psychomotor speed factor emerged as the best predictor of schizophrenics' hypothesis behavior.

Adaptation, Psychological↗