Neuroplacodes and their morphogenetical significance.
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Biomedical subjects
Publications and source records attributed to V Pospísilová.
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The development of the papillary terrain on the fingers and toes, palms and soles was studied in 36 fetuses of gestational age ranging from 9 to 26 weeks. Histologic methods on serial sections and studies of the dermal surface of the skin after removal of the epidermis (according to Okrajima) were the main approaches used. The morphogenesis of papillary crests is described at different developmental stages and factors involved in their origin are discussed.
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Fine structure of lymphoblastoid cell lines (LCL) derived from leukocytes of three patients with acute myelosis and one patient with undifferentiated acute leukemia were studied repeatedly by electron microscope. The majority of cells in all lines was of the same primitive lymphoblastic type as refered to in literature regardless to their origin. Morphology of the cells did not change with time of cultivation for several months, by freezing and thawing and by new recultivation after prolonged cryopreservation. No morphologic signs of contamination by viruses were found. No evident morphologic signs of differentiation to mature granulocytes or "mature" lymphocytes or plasmatic cells were observed.
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