In 23 healthy persons active in sports are tested circulating thrombocyte aggregates in venous blood. Their incidence is expressed as thrombocyte index (TI). In this group there is TI 0.8900 +/- 0.0193. TI compared with TI evaluated in 21 healthy persons not interested in their physical fitness (TI 0.7699 +/- 0.0162) is significantly different (p less than 0.01). The physically not active persons develop significant (p less than 0.01) higher incidence of circulating thrombocyte aggregates in comparison with the incidence in group of physically active persons. The authors use TI for monitoring antiaggregant therapy and for selection the risk group of patients, whose clinical situation requires antiaggregant treatment. The dosage of antiplatelet drugs is estimated according TI values to reach the level recorded in healthy physically active persons (TI greater than 0.7699 +/- 0.0162).

Adult↗

PubMedDate not supplied

Some interrelations between blood pressure parameters and claudication distances.

Sixty males and 2 females with the mean age of 58.1 years ranging from 39 to 80 years with atherosclerotic lesions of the arteries of lower extremities were studied. The claudication distance was subdivided into two segments: the first included the distance up to the onset of pain and the second one when the patients had to stop walking because of the severity of pain. The systemic systolic pressure and the poststenotic ankle pressure over both arteries on both calves by a Doppler ultrasound apparatus were measured and the individual pressure gradients were calculated. It was demonstrated that both claudication intervals were related to the poststenotic pressure as well as to the pressure gradient. The stepwise regression analysis showed a significant relationship between both distances and the lowest value of all ankle pressure measurements over four tibial arteries. The closest correlation (R = 0.98) was recorded between the initial and final claudication distance and it persisted even after the elimination of all pressure parameters.

Blood Pressure↗

PubMedDate not supplied

Significance of pedal arch for femoropopliteal vein bypass patency.

There are different opinions about the usefulness of preoperative arteriography. Therefore we resolved to show its importance for the distal runoff evaluation as well as for the indication and results of femoropopliteal vein bypasses. There were controlled 149 patients 1-5 years after femoropopliteal vein bypass implantations. Seventy six vein bypasses proved to be patent and seventy three were closed. The findings of preoperative arteriographies visualizating the whole arterial periphery, including the pedal arch arteries, were compared in both groups of patients. It was proved that the evaluation of the distal runoff by means of preoperative arteriography may be reliable and correct under condition of tibial and pedal arch arteries visualization. According to our experience, the preoperative arteriography can be performed in such a way to fulfil this indispensable condition. In rare case of preoperative arteriography repeated failure, it is the peroperative prebypass arteriography, which always is successful. In evaluating the distal runoff, there must be taken into consideration the whole arterial complex: tibial + pedal arch arteries. The patency of pedal arch seems to be more important than the number of patent tibial arteries. According to preoperative arteriographic findings, there is possible to distinguish three main types of distal runoff: (1) Sufficient runoff: whole pedal arch and 1-3 tibial arteries patent; (2) satisfactory runoff: partial pedal arch patency and 1-3 tibial arteries patent; (3) Unsufficient runoff: total pedal arch obliterations and 1-3 tibial arteries patency.

Aged↗