The main indication of thyroid hormone preparations is the treatment of hypothyroidism, ideally the goal of therapy is to restore the serum thyrotropin (TSH) concentration to a normal value. The optimal doses used to be stable, but several conditions may alter their requirements (reduced intestinal absorption, pregnancy,...). Levothyroxine therapy is also used in the benign nodular disease and after surgery in patients with thyroid cancer. The overtreatment with thyroxine and the problems related to bone mineral density seems of special importance.

Bone Resorption↗

PubMed1989

[Type II autoimmune polyglandular syndrome associated with empty sella turcica].

A case of autoimmune polyglandular deficiency type II (Addison's disease, primary hypothyroidism, primary hypogonadism of a lengthy evolution and vitiligo), associated with a progressive sellar enlargement, is presented.

Addison Disease↗

PubMed1988

[Diabetic neuropathic cachexia: report of 2 cases].

Explore the source record for details and available documents.

Aged↗