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Biomedical subjects

V R Agaronov

Publications and source records attributed to V R Agaronov.

4 recordsLinked to original sources
PubMedDate not supplied

[Dynamics of EEG-indicators in alcohol abstinence].

To study the possibility of discrimination of different periods of alcohol abstinence state (acute, subacute, and arrested) the brain electrical activity of 30 patients with chronic alcoholism was recorded from 24 sites of convexital scalp surface during the detoxication. The "Synchro-EEG" program package was applied for EEG processing using 840 parameters. Sets of state-specific characters were selected, and an integral parameter for estimation of the brain functional state was developed. Parameters of coherence of biopotentials in narrow frequency subbands turned to be of the greatest informative value. As compared to the normal state, in the acute period all the frequency components were changed. Their dynamics during detoxication was different. Delta and theta activity were normalized faster then the alpha and beta frequencies. The dynamics of the spatial synchronization foci reflected the recovery of consciousness and normalization of the brain functional state.

Adult↗
PubMedDate not supplied

[Multiple parameter comparative EEG analysis in alcoholism and narcotic dependence].

Multiparametric comparative analysis of spatial organization of EEG was carried out in 137 alcoholics and 131 heroin addicts. Common and different deviations from normal EEG (105 control subjects) were found. Global alterations of EEG spatial organization were observed in drug addicts (as compared to alcoholics). Such changes characterized increasing synchronizing effects of mesolimbic and brainstem structures on the brain cortex. The ethanol effects were more specific and asymmetric. Changes in EEG spectral-coherence characteristics were revealed in all frequency band, however, maximal changes took place in the high-frequency theta in drug addicts and in narrow-frequency alpha subranges in alcoholics. Different effects on the high-frequency EEG component (19.00-21.25 Hz) and information-energy index (coherence-to-spectral power ratio) suggest the difference influence of ethanol and heroin on emotional-motivational and cognitive processes as well as the level of consciousness. The obtained data on EEG discrimination of alcoholism and drug addiction (the inverse problem solution) on the basis of "specific" EEG patterns appear to have considerable promise in development of systems of occupational selection.

Adolescent↗
PubMedDate not supplied

[The spatial organization of the electrical processes of the cerebral cortex in a pathological attraction to alcohol].

The polymorphism of reaction to emotionally significant stimuli is discussed in the context of pathological incentive. Using the "Synchro-EEG" technique 41 patients and 11 healthy volunteers were examined. Analysis of the spatial organization of cortical electrical activity revealed three types of reactions in patients. Intergroup differences were reflected in generalized and local cortical processes (mainly, in the frontal regions of the left and temporo-parieto-occipital regions of the right hemispheres). They were probably related to the sign of emotions, behavioural and autonomic nervous tension and the attitude to the object of motivation ("approach-withdrawal"). This suggestion was substantiated by the finding that the aversive therapy can change the pattern of cortical processes. Intergroup differences were revealed not only in the reactive (to emotionally significant stimulus) but also in the background electrical activity. The groups were different in the dominance of different narrow-frequency processes in one group as compared to the other. These findings suggest determination of emotional reactions by the initial functional state of patients.

Adolescent↗