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Biomedical subjects

V R Kliachko

Publications and source records attributed to V R Kliachko.

71 records · Page 4Linked to original sources

[The nutrition of obese patients with diabetes mellitus].

The authors elaborated the main principles of diet therapy in diabetics with adipostiy: their weight was normalized with the aid of a low caloric diet with limited amount of carbohydrates and fats, but with the normal protein content. Two groups should be distinguished among the adipose patients: those without diabetic ketoaoidosis in the anamnesis or during the observation period; their diet differed by the extent of limiting of carbohydrates. As a result of the treatment carbohydrate metabolism was compensated with normalization of the glycemic curve; a tendency to normalization of lipid metabolism was noted; immunoreactive properties of the organism were increased.

Diabetes Complications↗

[Treatment of diabetes mellitus with long-acting biguanides].

The paper discusses of the results of treatment with preparations of phenylethylbiguanide (dibotin, meltrol, dipar, dibophen-retard), of butylbiguanide (silubin-retard, buforming-retard) and of dimethyl-biguanide (glucophage-retard). All these preparations were of prolonged action. The treatment was carried out in 242 patients. The saccharolytic action of the active agent contained in one tablet of each type of biguanide was approximately the same. Biguanides of prolonged action were highly effective in obese patients with diabetes mellitus of moderate severity. The best results were obtained in complex treatment with biguanides of prolonged action together with sulfonylurea preparations of the second generation. There were noted almost no toxic reactions from the use of biguanides up to 2 tablets a day.

Adult↗