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Biomedical subjects

V R Minocha

Publications and source records attributed to V R Minocha.

At least 19 recordsLinked to original sources

Lateral sacral meningomyelocele as a gluteal swelling--an unusual presentation.

Paravertebral meningoceles are rare examples of craniospinal dysraphism. A young boy presented with a cystic swelling over left gluteal region with lumbosacral scoliosis. On exploration, he was found to have a laterally placed sacral meningomyelocele. The presence of an unusually located meningocele should be suspected when a paravertebral mass is associated with neurological deficit or deformity of the spine.

Buttocks↗

Hindgut duplication--case report and literature review.

Colonic duplication is a rare congenital abnormality that can present diagnostic difficulties. A case of duplication of the entire large bowel and terminal ileum is presented, and a framework for diagnostic work-up and treatment options in these patients is discussed.

Colon↗

Ureteric stricture with a perirenal urinoma treated by ureteric replacement with appendix.

Appendix has routinely been utilized by the urologists as an intermittent catheterization route to empty a continent urinary reservoir. However it is utilized very rarely for ureteric substitution. We present here our experience with the use of an appendicular conduit for substitution of a complete ureteric stricture and discuss the implications of its use for ureteric reconstruction.

Adult↗

Hydronephrotic obstructed kidney mimicking a congenital multicystic kidney: case report with review of literature.

OBJECTIVE: To report a case of obstructed hydronephrotic kidney mimicking a multicystic kidney and to review the literature regarding differentiation of the hydronephrotic variant of multicystic kidney from the obstructed hydronephronic kidney. To suggest a possible algorithm in distinguishing them. METHODS: We have reported a case of a 35-year-old male who presented with dull aching pain and a palpable right-sided cystic flank mass of several years duration. The initial workup suggested a nonfunctioning multicystic kidney while the operative findings and histopathology were suggestive of an obstructed hydroenphrotic kidney with pyelonephritic changes. We searched the literature using the key words hydronephrotic dysplastic kidney and multicystic kidney. RESULTS: A detailed literature search did not reveal any such publication describing the differentiation of the hydronephrotic multicystic dysplastic kidney from the obstructed hydronephrotic kidney of pelviureteral obstruction. We reviewed the existing literature on this subject, on the basis of which, we have suggested a six-stepladder approach to distinguish such cases. CONCLUSION: By using the 6 step ladder protocol algorithm suggested by us one can attempt to distinguish the hydronephrotic variant of multicystic dysplastic kidney from the hydronephrotic kidney due to pelviureteral obstruction in patients presenting with a symptomatic cystic flank masses of renal origin. Differentiation between the two may be difficult at times due to the medial/central placement of cysts in the former. This is necessary since renal salvage may be possible in the latter while timely nephrectomy may be considered in the former to prevent against the hazards of leaving behind a dysplastic kidney in situ.

Adult↗

Effect of partial ileal bypass on the lipid profile in the hyperlipedemic rabbits.

The hypocholesterolemic effect of partial ideal bypass was studied in two groups of healthy albino rabbits. Both groups of rabbits were made hypercholesterolemic by feeding them cholesterol suspended in groundnut oil (1 ml/kg bw) at a dose of 100 ml/kg bw/day for one week. Group I rabbits were subjected to partial ileal bypass and group II rabbits were sham operated. Weekly estimation of serum lipid profiles were done for four more weeks while continuing cholesterol feed. After end of 5th week, it was found that partial ileal bypass not only prevented but also brought down its level from 132.8 mg% to 44.8 + 2.24 mg%, as compared to sham operates group where cholesterol level was 279 + 5.84 mg%. There was improvement in other parameters of lipid profiles namely HDL-C & LDL-C + VLDL-C and TAG.

Animals↗

Primary actinomycosis of the abdominal wall.

A rare case of primary actinomycosis of the abdominal wall presenting as a tumour is described. The patient responded to penicillin therapy well. A brief account of the literature is included.

Abdominal Muscles↗

Malignant parotid cyst.

A case of primary malignant cyst of the parotid gland is described, and the possible origins of such cysts are discussed.

Aged↗

Review of a hospital experience of enterocutaneous fistula.

A retrospective analysis of records of 46 patients with enterocutaneous fistulas treated over a period of three and half years has been done. There were 28 males and 18 females, with 80% of patients being in age group of 25-35 years. Forty-five patients were postoperative and in one patient fistula occurred spontaneously. Tuberculosis was the most common underlying pathology, seen in 32.6% followed by enteric fever in 23.9%. The small intestine was the most common site for the origin of fistula, seen in 34 patients (73.9%). There were 22 patients with high output fistula and 24 with low output. For high output fistulas, enteric fever was the most common cause (45%) and ileum was the most site of origin (82%). Low output fistulas were mainly of tubercular aetiology (62%) and involved ileum in 62% of cases. Nineteen out of 22 patients of high output fistulae had sepsis. Fourteen of these had generalised peritonitis (63%) and 5 had localized intra-abdominal collections (27%). Spontaneous closure occurred in 45.6% of patients on conservative management and 37% patients underwent surgical intervention. The overall mortality was 30.4%. High output fistulae had mortality figure of 54.5% and low output fistulas 8.4%. Mortality in relation to sepsis was 63%. No patient with sepsis and without surgical intervention survived. Following surgical intervention mortality was 50% in patients who showed evidence of sepsis. Early and effective control of sepsis is the most important factor determining outcome in patients of enterocutaneous fistula.

Adolescent↗

Massive amebic liver abscess--an unusual presentation.

A 40-year-old woman presented with a huge lump in the right half of the abdomen and irregular menses. Ultrasonography showed a cystic lump with septations, extending from the upper abdomen to the pelvis; the right ovary was not seen. On exploration, there was a large cyst arising from the right lobe of the liver; the aspirate was bilious. Since the cyst wall was adherent to retroperitoneal structures, complete excision was not possible. A roux-en-Y loop of jejunum was anastomosed to the cyst wall. Biopsy of the wall showed inflammatory granulation tissue with trophozoites of Entamoeba histolytica. She was treated with metronidazole, and recovered uneventfully.

Adult↗