[Structure of the vascular network on the surface of the human cerebral hemispheres during the second half of intrauterine and the early postnatal period of development].
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Biomedical subjects
Publications and source records attributed to V R Purin.
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Local cerebral blood flow (1CBF) measured by hydrogen saturation technique, and cerebral blood volume (CBV) observed by photoplethysmographic method were investigated in unanesthetized newborn rats. 1CBF in newborn animals was found to be much lower than in the adult ones. In contrast to adult animals, CO2 inhalation in newborn rats failed to increase 1CBF. CBV also remained constant during the CO2 inhalation.
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It was shown by the plethysmographic method that, in contrast to adult animals, in the newborn rats the blood vessels of the cerebral hemispheres and of diencephalon while displaying a distinct response to oxygen, failed to react to carbon dioxide, the latter being attributed to the low carbonic anhydrase activity in the tissues of these portions of the brain.
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