Biomedical subjects
Publications and source records attributed to V R Veber.
The authors revealed that actual prevalence of various COLD exceeded the registered value 3.3 times. The actual prevalence appeared to be under influence from tobacco smoking habits distribution, effects of industrial dust pollutants, chronic nasopharyngeal infections, respiratory infections, age, and atmospheric pollution.
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The article covers differential diagnostic features of pulmonary tuberculosis and pneumoconiosis in workers engaged into mullite refractories production. The authors suggest that the disease courses as a new form of lung disorder--mullitosis.
The authors evaluate clinical peculiarities of chronic bronchitis, silicotuberculosis and pneumoconiosis (mullitosis) in workers exposed to highly aluminiferous clay.
As many as 56 healthy women and 45 women of reproductive age, suffering from essential hypertension (EH) were examined for the effect of ovarian cycle phases on vegetative regulation of central hemodynamics and pharmacodynamic effects of hemiton. The healthy persons in the phase of proliferation (I) and secretion (III) demonstrated the predominance of the parasympathetic tone and high responsiveness of the autonomic nervous system (ANS). The phase of ovulation (II) and the menstrual phase (IV) were characterized by the high sympathetic tone and low responsiveness of both parts of the ANS. The lowest values of the stroke and minute blood volumes were detected in phase II, whereas the highest ones in phase IV. In EH patients, the recurrence of ANS function was disturbed, the dynamics of the parameters became opposite to that seen in healthy persons. Hemiton produced the maximal hypotensive effect in phases I and II, the minimal one in phases III and IV. In phases I and III, the drug minimized the cardiac output; the general peripheral resistance was reduced in phases I and II; in phase IV, the drug did not provoke any significant changes in hemodynamics. The data obtained permit a differentiated approach to the distribution of the hemiton dose required for the treatment course in EH women of reproductive age.
Isoptin and obsidan were demonstrated to cause a significant increase in exercise tolerance in patients with Stages I and II hypertensive disease. The response of blood pressure to isoptin and obsidan was virtually identical, yet isoptin acted longer. When obsidan was administered, there was a decrease in specific peripheral vascular resistance with a stepwise elevation of blood pressure, whereas isoptin promoted its slight rise with maximally elevated blood pressure. Isoptin administration prevented brain hyperperfusion at maximum blood pressures.
The hemodynamic effects of anaprilin at various hours of the day in patients with essential hypertension depends on the initial type of central hemodynamics. The negative inotropic effect of anaprilin in the hyperkinetic type is revealed with high frequency at all hours of the day, in the eukinetic type at 10 p. m. and in the hypokinetic type at 5 p. m. In the initial hyperkinetic type of hemodynamics the hypotensive effect of anaprilin is pronounced at midday and 10 p.m., in the eukinetic type at 7 a. m., midday and 5 p. m. and in the hypokinetic type at 7 a. m.
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Healthy men, representatives of the indigenous population and newcomers, have some differences on the part of the vegetative and cardiovascular system. The newcomers mostly show coronary atherosclerosis and predominance of the tone of the ergotropic system. The cardio- and hemodynamic differences manifest by more pronounced shifts on making orthostatic and exercise tests, by an appreciable rise of myocardial contractility and energy expenditure for blood translocation.
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The leukocyte intoxication index (LII) was examined in 292 patients with acute abscesses, pulmonary gangrenes and pneumonias. The more extended and severe the process, the higher were the LII parameters. It was the highest in patients with pulmonary gangrene, the lowest with focal pneumonia. The index is considered to represent the dynamics of the process allowing to timely diagnose the development of the disease and its complications. A simple formula of LII is proposed which makes its application easier.
The development of essential hypertension is accompanied with vegetative shifts which differ in male and female patients. Male patients show simultaneous vegetative parasympathetic and adrenomedullary sympathoadrenal activation, while sympathetic neurogenic effects prevail considerably in females. Essential hypertension can be distinguished from symptomatic renal hypertension by a sharp change in vegetative reactivity and disrupted circadian rhythm of vegetative control as reflected in the sympathetic activity peak being shifted to evening and night hours.
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