PubMed Health⌕ Search

Biomedical subjects

V Rakoff

Publications and source records attributed to V Rakoff.

13 recordsLinked to original sources

Changes in local cerebral glucose utilization after chronic ethanol in rats.

Local rates of cerebral glucose utilization were investigated in ethanol-treated rats using the 2-deoxy[14C]glucose method. Rats received ethanol in drinking water for 3 h each day. After 4 days of exposure to 2 or 4% ethanol (v/v), there was a general tendency toward increased local cerebral glucose utilization. In contrast, after 28 days of exposure to concentrations to 10% ethanol a general depression of cerebral glucose metabolism was observed. Brain regions showing significantly reduced glucose utilization rates in the 28-day group included components of the extrapyramidal system, several thalamic and hypothalamic nuclei, and forebrain limbic structures. A group of animals tested 7 days after discontinuation of ethanol showed essentially normal rates of local cerebral glucose utilization, indicating that alterations in regional brain glucose metabolism induced by this particular regimen and duration of ethanol administration were largely reversible.

Alcoholism↗

The behavioural sciences and undergraduate education in psychiatry.

The Behavioural Sciences are becoming increasingly important in medical education and in medical treatment. But medical students and the profession generally, appear to have difficulty accepting behavioural sciences as a valid part of the curriculum and in the practice of medicine. One of the reasons for this may be related to a narrow definition of the physician's social role in the years following the adoption of the Flexner Report in 1911 which emphasized the model of the physician/scientist. The perennial model of the physician occupying a social role in which science is used to increase and rationalize responsiveness to suffering has been eroded in favour of the pursuit of the scientific as the essential goal of medicine. The newer, "softer", sciences of anthropology, ecology, economics, psychology and sociology have not fitted into the professional self-perception of the medical role. Furthermore, some departments of behavioural science have adopted an intellectual stance at times antagonistic to the rest of the medical school emphasizing the shortcomings of the profession in its delivery of health care. The aspirant medical student may have been disaffected by teachers who do not embody acceptable role models. Students should receive specific instructions in the social role of the physician, physicians should be actively involved in teaching the behavioral sciences and the curriculum should at all times emphasize the relevance of the behavioural sciences to the daily practice of medicine.

Behavioral Sciences↗