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Biomedical subjects

V Reid

Publications and source records attributed to V Reid.

At least 19 recordsLinked to original sources
PubMed2002

Information sessions for outpatients referred to a hospital Nutrition and Dietetic Service for cholesterol lowering advice.

AIM: To assess the feasibility of recruiting outpatients referred for cholesterol lowering advice to attend a 1-h evening information session provided by a hospital dietitian and to evaluate the service. METHOD: A Cholesterol Information Session was held on one evening each month between April and September 2000. Patients referred to the Nutrition and Dietetic Service for cholesterol lowering advice were sent appointments for these sessions by post instead of a one-to-one daytime appointment with the dietitian. At the session, the dietitian explained what cholesterol is and gave advice about the healthy eating and lifestyle changes needed to control it. Video material and literature were used to support verbal information. Questions were encouraged throughout the session. RESULTS: Thirty-four patients were sent appointments. Twenty-seven (79%) attended, 10 of whom were accompanied by a spouse/partner/carer/family member. All patients who attended completed evaluation forms. There was a high level of satisfaction with the sessions. Twenty-six patients (96%) said they liked the way the session was run and found the advice and videos helpful. Twenty-five patients (93%) preferred the evening appointment to a day time one. Patients who attended with a spouse/partner/carer/family member indicated it was helpful to them and the accompanying person. Feedback through patient comments was positive. The seven patients (21%) who did not attend the sessions made contact with the dietetic service. CONCLUSION: As a result of the positive outcome of the evaluation, the Cholesterol Information Session is continuing as a service to patients. It provides a facility outside the usual hours of outpatient services and can readily accommodate accompanying people. The information session uses the group format, which may be applicable to other specialist areas of the Nutrition and Dietetic service in the future, such as diabetes management.

After-Hours Care↗
PubMed1999

Proximal sensory neuropathies of the Leg.

This article addresses the proximal sensory neuropathies of the leg, concentrating on those nerves that are purely sensory or have a predominately sensory onset. These include the lateral femoral cutaneous nerve, the ilioinguinal nerve, the genitofemoral nerve, and the posterior femoral cutaneous nerve. The obturator and femoral nerves are also summarily mentioned with respect to their sensory symptoms.

Diagnosis, Differential↗
PubMed1998

Hydrostatic reduction of acute intussusception. A prospective study.

Data were collected prospectively on 57 Jamaican children presenting with 62 episodes of acute intussusception over a two year period, for whom operative and hydrostatic methods of reduction were employed. 31 (54%) of 57 episodes were reduced successfully using barium (42), saline (11) and air (4) hydrostatically. Among the 31 other episodes, 15 had ileo-colic intussusception, seven caeco-colic, six ileo-ileo-colic and one ileo-ileal. Two patients had spontaneous reduction discovered at surgery. There were two episodes of barium hydrostatic perforation of the colon leading to death in one patient. Hydrostatic reduction is recommended as the first therapeutic option for acute intussusception because it spares the patient a major operative procedure when successful.

Acute Disease↗
PubMed1996

Positive selection by thymic nurse cells requires IL-1 beta and is associated with an increased Bcl-2 expression.

A temperature-sensitive line of thymic nurse cells (tsTNC-1) that maintains the ability to selectively internalize immature alpha beta TCRloCD4+CD8+ thymocytes in vitro was used in long-term coincubation experiments to determine nurse cell function during the process of MHC restriction. The thymocyte subset released from its association with TNCs contained both viable and apoptotic cells. The cells that remained within intracytoplasmic vacuoles died through the process of programmed cell death. Surviving or rescued thymocytes in the released population displayed an increase in Bcl-2 protein expression. The rescue activity of TNCs was drastically reduced with the addition of antibodies against either class I or class II MHC antigens to cocultures. A subset of the TNC-rescued population matured from the alpha beta TCRloCD69- phenotype to alpha beta TCRhiCD(69+)-expressing cells only when IL-1 beta was added to cocultures. These results suggest that TNC rescue of early double-positive thymocytes from apoptosis is associated with an interaction between the TCR and the MHC and the onset of Bcl-2 expression. Maturation of thymocytes within the TNC-rescued population requires the costimulatory effects of IL-1 beta.

Animals↗
PubMed1996

Control of Culex quinquefasciatus in pit latrines, using shredded, waste polystyrene.

As an alternative to the use of commercially available, expanded-polystyrene beads, a study was made of the effectiveness of shredded, waste polystyrene (SWAP) for the control of Culex quinquefasciatus. The relevant physical properties of the SWAP were first investigated in the laboratory. Then, under field conditions in wet pit latrines, mosquito emergence rates were measured before and after application of the material. In the laboratory, when compared with the commercial product, the irregular shape of the SWAP particles greatly reduced their capacity to spread over the water surface and the interstitial air spaces also permitted respiration and development of mosquito larvae. Nevertheless, under field conditions, with careful application of the SWAP over the water surfaces in wet pit latrines, almost complete control of mosquito breeding was observed within a few days. This was sustained for 60 days, at which time observations were discontinued. SWAP appears to offer an effective, cheap and readily available alternative to the commercial product for the control of C. quinquefasciatus. The practicality of using it in community-based, mosquito-control programmes warrants further study.

Animals↗
PubMed1992

Thymic nurse cells exclusively bind and internalize CD4+CD8+ thymocytes.

Thymic nurse cells (TNC) contain 20-200 thymocytes within specialized vacuoles in their cytoplasm. The purpose of the uptake of thymocytes by TNCs is unknown. TNCs also have the capacity to present self-antigens, which implies that they may serve a function in the process of thymic education. We have recently reported the development of thymic nurse cell lines that have the ability to bind and internalize T cells. Here, we use one of these TNC lines to identify the thymocyte subpopulation(s) involved in this internalization process. TNCs exposed to freshly isolated thymocytes bind and internalize CD4 and CD8 expressing thymocytes (CD4+CD8+ or double positives) exclusively. More specifically, a subset of the double-positive thymocyte population displayed binding capacity. These double-positive cells express cell surface alpha beta type T cell antigen receptor (TCR), as well as CD3 epsilon. Binding was not inhibited in the presence of antibodies against CD3, CD4, CD8, Class I antigens, or Class II antigens. These results describe two significant events in T cell development. First, TNCs exclusively bind and internalize a subset of alpha beta TCR expressing double-positive T cells. Also, binding is facilitated through a mechanism other than TCR recognition of major histocompatibility complex antigens. This suggests that thymocyte internalization may be independent of the process used by TNCs to present self-antigen.

Animals↗
PubMed1987

Nutrient intakes and dietary compliance in cardiac patients: 6-year follow-up.

Changes in nutrient intakes which were recorded in the diets of cardiac patients at 1-year follow-up were maintained at 6-year follow-up, with the exception of fibre intake. Twenty-three patients, 60 per cent of the original study, were available for assessment at 6-year follow-up. The majority of these patients (74 per cent) had been classified as good compliers at 1-year follow-up. They had maintained the nutrient intakes observed at 1-year follow-up, except for fibre intake which had been reduced. Nutrient intakes of the small number of poor compliers (26 per cent) tended to deteriorate between 1- and 6-year follow-up. Body weight, which was reduced at 1-year follow-up, had increased to initial levels at 6-year follow-up for the total group. Poor compliers showed the greatest increase in weight. Serum cholesterol levels showed little change throughout the study for all patients. Compliance at 1-year follow-up appeared to determine compliance over the longer follow-up period for the study patients and especially for good compliers. More attention needs to be given to evaluating the factors which influence compliance, in particular dietary compliance.

Cardiovascular Diseases↗
PubMed1985

The Rorschach Comprehensive System Egocentricity Index in psychiatric inpatients.

This paper reports an exploratory study of potential correlates of Exner's Rorschach Egocentricity Index, a measure of self-focusing, in a sample of 70 psychiatric inpatients. We examined the relationship of the Index of the MMPI Ego Strength scale and to other MMPI and Exner Comprehensive System Rorschach variables, using Pearson Product-Moment correlations with partialling of the number of Rorschach responses. There were seven meaningful significant correlations between the Index and Rorschach variables: M, FM, X +%, F +%, Lambda, D, and A%. The Index-MMPI correlations were not significant. Sex differences and differences between these intercorrelations and some reported by Exner (1983) are discussed.

Adolescent↗
PubMed1984

Factors affecting dietary compliance in coronary patients included in a secondary prevention programme.

Nutrient intake was altered favourably in the diets of 38 cardiac patients who were followed up for 1 year as part of a rehabilitation programme. Total energy intake was reduced from 3540 kcal (14.9 MJ) to 2484 kcal (10.4 MJ). Fat intake was reduced from 41 to 37 per cent of energy intake with an accompanying increase in P : S ratio from 0.18 to 0.60. Cholesterol intake was reduced from 564 to 332 mg. Carbohydrate was increased from 38 to 41 per cent of energy intake with an increase in fibre intake from 18 to 24 g. The energy contributed by alcohol was reduced from 6 to 5 per cent. Patients varied in their compliance but all patients made some changes in their dietary intake. Changes in body weight, serum cholesterol levels, cigarette-smoking status and levels of physical activity tended to correspond with the recorded changes in nutrient intake. A low level of education, low socio-economic group, lack of understanding of the illness by the patient and inadequate communication were associated with reduced compliance. Initial motivation and anxiety levels in hospital had less effect on compliance.

Adult↗
PubMed1984

Sequelae of mild closed head injuries.

Thirty-nine minimal to mild closed head injuries without neurological signs were evaluated by a series of clinically available psychometric tests to determine the presence of identifiable intellectual deficits, rate of recovery, and personality or occupational changes. Even minimally head-injured patients suffer measurable cognitive deficits and occupational and behavioral changes.

Adolescent↗
PubMed1983

Follow-up of sixty-one physicians after psychiatric treatment.

Reported the results of a direct follow-up of 61 physicians who had been hospitalized for emotional impairment during 1969-1978. As of the fall-winter of 1979-1980, 35 physicians were in productive practice; 8 had died of purely medical causes; 5 had committed suicide; 2 were over age 65 and retired; 6 were not practicing for other reasons; 2 were physically disabled; and 3 could not be located. Recovery rate varied from 57% to 71% depending on the criteria used in calculating the ratio. Our outcome rate accords with those reported previously. Interviews with surviving physicians revealed that some important factors in recovery were rest and recuperation; spirituality, AA, and NA; modification in workload; support of colleagues; and constructive use of threat of loss of licensure.

Adult↗