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Biomedical subjects

V S Dubrovskiĭ

Publications and source records attributed to V S Dubrovskiĭ.

At least 19 recordsLinked to original sources
PubMed1998

[The surgical treatment of heart defects in active infectious endocarditis].

AIM: To elucidate significance of early diagnosis and results of surgical treatment of valvular defects in active infectious endocarditis (AIE). MATERIALS AND METHODS: Surgical outcomes were analyzed for 437 AIE patients with active AIE. The operation was made 10 months, on the average, after AIE onset. RESULTS: Total hospital lethality made up 11.2%. Total 5-year survival with account for hospital death was 77-80% in replacement of one valve and 61.6% in replacement of two valves (mitral and aortic). In natural course of the disease it was 16%. CONCLUSION: There was a direct relationship between hospital lethality and admission condition of the patients, advance of the inflammation. This urges early AIE detection and performance of operation before development of irreversible changes in the myocardium and other organs.

Endocarditis, Bacterial↗
PubMed1992

[Active valvular infective endocarditis: problems of surgical treatment].

The authors analyze the results of surgical treatment of patients suffering from active endocarditis with impairment of the mitral, aortal and tricuspid valves and their combinations in 242 patients operated on during 1969 to 1989. The total hospital mortality is at the level of world statistics and constitutes 15.3% (37 patients died). The main cause of the hospital mortality was acute progressive heart failure (48.6%). The long-term results of the surgery were examined in 202 patients. By the 5th observation year the total survival was 73.2%, the stability of good results 83.6%. The defined grades of the activity of infectious process play an important role in the diagnosis and treatment of patients with active valvular infectious endocarditis.

Adolescent↗
PubMed1991

[Surgical treatment of mitral and tricuspid valve defects].

The results of surgical treatment of 265 patients with mitral-tricuspid valvular diseases are analysed. The operations were carried out in the period from Jan. 1, 1977 to Jan. 1, 1990 with various plastic procedures on the tricuspid valve. Hospital mortality was 13.2%. The late-term results were studied in follow-up periods of 6 months to 12 years in 207 (90%) patients. The results were good in 187 (75.9%), satisfactory and poor in 28 (13.5%) patients; 22 (10.6%) patients died. With the hospital losses taken into account, 5-year survival came to 73% and 10-year survival to 54%. Stability of good postoperative results was 79% by the 5th year and 49% by the 10th year. Among the surviving patients 85% are related to functional classes I and II and lead an active life. Plastic operations on the tricuspid valve can be undertaken in 92% of patients with mitral-tricuspid valvular diseases; they produce good late-term results in most cases, ensure stable normalization of hemodynamics, and should be performed more often in clinical practice.

Adult↗
PubMed1990

[Reoperations after insertion of heart valve prosthesis].

The authors analysed 167 repeated operations after heart valve prosthetics, which were conducted from 1978 to 1988. The operations were undertaken for the second time mainly in a severe contingent of patients. The reasons for the repeated operations were specific complications according to which 2 groups of patients were set apart: with dysfunction of the prosthesis of noninfectious origin and with prosthetic endocarditis. Study showed that repeated operative intervention undertaken in time reduces considerably its risk and produces a stable positive effect in most cases.

Adolescent↗
PubMed1988

[Possibilities of cardiac surgery in the treatment of active valvular infectious endocarditis].

The results of surgical treatment of 142 patients with active valvular infectious endocarditis are reviewed. Hospital mortality was 15.5% (22 patients died). Follow-up covered 6 months to 14 years (with an average of 3.5 years) in 108 patients. Ten (9.3%) patients died over this period, and 11 (10.2%) showed indifferent or poor results of surgery. Within 5 years, total survival rate was 74.4%, including hospital mortality, and good late results were seen in 76.8% of the discharged patients. Surgical treatment of active valvular infectious endocarditis is shown to be a fairly effective method and should be used on a larger scale in clinical practice.

Adolescent↗
PubMed1981

[Surgical treatment of multiple heart valve defects].

The article deals with the study of problems of the surgical treatment of patients with multivalvular heart diseases. Problems of myocardial protection, the methods for correcting tricuspid disease, and the attitude towards attendant valvular diseases depending on their severity are discussed on the grounds of the analysis of hospital fatality rate in a group fo 505 patients who underwent one-stage correction of two or three defective heart valves and the appraisal of late results. Analysis of the late results indicates that a more radical approach to the surgical treatment of mitral valvular disease is necessary and that marked relative insufficiency and all forms of organic tricuspid disease must be corrected without fail.

Adolescent↗
PubMed1980

[Surgical procedure in repeated operations on the mitral valve].

The experience in repeated operations on the mitral valve is generalized and the results of 340 repeated closed mitral commissurotomies and 124 operations performed under conditions of extracorporeal circulation are analysed. Hospital mortality in open operations is still rather high (20%), whereas the stability of good results in follow-up periods of up to 5 years is 53.9%. At the same time, the results of repeated closed operations are quite acceptable; low hospital mortality (4.7%), relatively satisfactory stability of good results (55.3% in follow-up periods of up to 10 years). The authors believe that a differentiated approach to the choice of the method for repated operations on the mitral valve is necessary.

Extracorporeal Circulation↗
PubMed1979

[Clinical study of oxacillin for intravenous administration in heart surgery after operations with artificial circulation].

Intravenous sodium oxacillin of Soviet production was subjected to clinical trials in 50 cardiosurgical patients. The patients were operated under conditions of artificial circulation. The antibiotic was used for prophylaxis and therapy of the postoperative pyo-inflammatory complications. In the group of the patients observed no lethal cases due to the post-operative infection were registered.

Adolescent↗