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Biomedical subjects

V S Genes

Publications and source records attributed to V S Genes.

At least 19 recordsLinked to original sources
PubMed1994

[Lipid metabolism and blood coagulation system function in patients with the late sequelae of closed craniocerebral trauma].

Long-term follow-up of the subjects who have suffered closed brain injury showed that in comparison to matched controls the injured young subjects demonstrated abnormalities in lipid metabolism and coagulation tending to atherosclerosis. The limits of the values by which the patients significantly differed from the controls as well as 7 specific for the patients signs of lipid metabolism and coagulation impairment have been determined. From 1 to 5 specific indications registered in 67 +/- 5% patients allowed the diagnosis in them of the injury sequelae. The mechanisms of the above atherosclerotic shifts may work through neuroregulatory derangements common for brain injury and atherosclerotic encephalopathy and enhancement of atherosclerosis course by the craniocerebral damage.

Blood Coagulation↗
PubMed1991

[Immunity and middle molecule levels in the blood of patients with brain tumors].

The immunity indicators (T general, T active and B lymphocytes, IgA, IgM and IgG, phagocytosis intensity and activity) and blood content of medium-size molecules (MSM) were studied in patients with brain tumors. Immunity disturbances were revealed in 96 +/- 4% of the patients whereas the increase of the content of MSM was detected in all the patients. The ratio of the absolute count of B lymphocytes to the count of T general lymphocytes (B/T) was offered for use. The magnitude of the ratio equal to 0.47-0.85 turned out characteristic of malignant tumors. The presence of MSM ranging within 0.390-0.480 units was common to the same tumors. The simultaneous demonstration of the characteristic magnitudes of the B/T and MSM in the patient permits one to reliably differentiate between malignant and benign brain tumors. The high magnitudes of MSM are prognostically unfavourable as regards the patients' survival after surgery.

Adolescent↗
PubMed1981

[Application of the characteristic interval method to differential diagnosis between the depressive phase of manic-depressive psychosis and reactive depression].

Using V. S. Genes' method of characteristic intervals 112 gradations of 36 different factors were analyzed in women under 40 years of the age with diagnoses of the depressive phase of manic-depressive psychosis (50 patients) and reactive depression (38 patients). The authors discovered 11 differential-diagnostic features relatively specific for the depressive phase of manic-depressive psychosis, and 13 features specific for reactive depression. As a result of a comprehensive analysis of these features a system for diagnostic differentiation between these conditions has been developed. This system makes it possible to diagnose correctly the depressive phase of manic-depressive psychosis in 78% of cases. In 20% of the cases the diagnostic solution remains uncertain, and in 2% erroneous.

Adjustment Disorders↗
PubMed1981

[Diabetic neuropathy and lesion of the vessels].

Data from the literature concerning the frequent lack of correlation between the clinical manifestations of diabetic neuropathy on the one hand and the morphofunctional status of the appropriate nerves, disorders in carbohydrate and lipid metabolism, and the influence of antidiabetic therapy on metabolism and the clinical picture of diabetic neuropathy on the other, are presented. In this connection, abundant evidence of frequent affection of various blood vessels, particularly small and smallest, in diabetic neuropathy is considered. But even these data attest to a non-infrequent lack in diabetic neuropathy of the involvement of the appropriate vessels, particularly the lack of basal membrane thickening which is a most common indication to the diabetic involvement of capillaries. Attention is drawn to the possible role of genetic heterogeneity of people with regard to the development of various forms of diabetic neuropathy.

Adult↗