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Biomedical subjects

V S Panuntsev

Publications and source records attributed to V S Panuntsev.

13 recordsLinked to original sources

Arteriovenous malformation of the cervical spinal cord with unusual drainage into the cranial cavity.

A case of arteriovenous malformation of the cervical cord 20 years in duration, studied angiographically, using computerized tomography scans and magnetic resonance images, as well as findings at autopsy are presented. The malformation was fed by the right vertebral artery, which entered a giant saccular aneurysm-like structure located subdurally on posterior spinal cord surface, and terminated there. Plenty of vessels of various diameter were found in the spinal cord substance at this level (C4-C6). Blood flow drained via a grossly enlarged vein at the anterior spinal cord fissure into cranial cavity, where varicose posterior fossa veins could be clearly seen and a single vertebral artery was present.

Adult↗

[Intracranial cavernous angiomas: ultrastructural and immunochemical study].

43 brain cavernous angiomas (CA) were clinically and morphologically studied. The presence of smooth muscles and endotheliocytes in the trabeculae was confirmed. The sources of blood supply and the nature of medullary changes at the CA periphery were clarified. The hypothesis of CA hormonal dependence has been rejected.

Adolescent↗

[Embolization of cerebrovascular aneurysms with controlled microspirals (complications and technical problems)].

The paper summarizes five-year experience with mechanically detachable microspirals for embolization of 62 arterial aneurysms in 59 patients. The complications and technical problems associated with both the specific features of this technology and anatomic types of the structure of vessels and aneurysms are described. Methods for the prevention and treatment of these complications are proposed.

Adolescent↗

[Early and late results of the intravascular treatment of cerebral aneurysms with a detachable balloon-catheter].

The paper analyzes the outcomes of intravascular treatment in 87 patients with cerebral aneurysms with separable a balloon catheter with a valve device. In the cold and hemorrhagic periods, mortality rates were 6.4 and 40%, respectively. The postoperative follow-ups lasted 1 to 17 years (mean 7.7 years). Recurrent subarachnoidal hemorrhage (SAH) was noted in 6.5% of cases, with not earlier than 4.5 years after intervention. The remaining patients (even with partial aneurysmal occlusion) had no recurrent SAH.

Catheterization↗

[Temporal arterial clipping and autoregulation of cerebral blood flow at surgery for intracranial aneurysms].

Preoperative dynamic autoregulatory responses in 20 patients considered as candidates for vessel temporal clipping (TC) and/or arterial hypotension (AH) at surgery for aneurysms were studied by the thigh cuff method. Normal autoregulatory responses at a regulation rate (RoR) of 20.4 +/- 2.8%/s were found in 10 patients > 30 days after subarachnoidal hemorrhage (SH) while RoR was 12.5 +/- 2.5%/s in 10 other patients (30 days, grade III WFNS showed autoregulation impairment. TC and/or AH were proceeded in 17 operated patients. One postoperative death was due to pulmonary embolism. Two poor results with persistent neurological disorders at discharge were associated with TC but in 1 patient. This patient had severe vasospasm and the lowest RoR (9%/s). There were no TC and/or AH postoperative complications in other 14 patients. All of them and 3 other patients with direct aneurysm clipping had a fair outcome.

Brain↗

[Quantitative characteristics of cerebral blood flow and gas exchange in cerebral contusions].

Statistical characteristics of blood flow and gas exchange parameters in patients with craniocerebral injury grouped in a different manner according to the severity of the contusion, the state of consciousness, and the general condition were obtained by electric computer processing of the results of studying hemispheric blood flow by means of 133Xe clearance in 86 cases, oxygen consumption by the brain in 36 cases, and carbon dioxide excretion by the brain by Van Slyke's method in 75 cases. A close correlation was revealed between the state of the patient's consciousness and the parameters of cerebral blood flow and gas exchange; compression in severe brain contusion was found to have a statistically significant effect on cerebral blood flow and gas exchange.

Brain Concussion↗

[Functional significance of the internal carotid arteries and collateral circulation in cerebral aneurysm surgery].

The functional significance of the internal carotid artery was appraised in 18 patients with arterial, in 8 with arteriovenous aneurysms and in one patient with atherosclerosis of the cerebral vessels. The appraisal was based on changes in the intracarotid pressure and regional cerebral blood flow (quantitative criteria) in temporary occlusion of the internal carotid artery with a double-lumen balloon catheter and on the change in the patients' clinical condition during temporary or stationary arrest of blood flow through the internal carotid artery that is studied. In large arteriovenous aneurysms, the collateral circulation ensures adequate blood supply to the brain tissue on the side of temporary occlusion of the internal carotid artery. The functional importance of the internal carotid artery in patients with arterial aneurysms points to the possibility of reconstructive operations in aneurysms of the internal carotid artery which are inaccessible for direct intervention. However, it is expedient in every case to make sure that the operation is safe by preoperative appraisal by means of the suggested method.

Adult↗