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Biomedical subjects

V S Petrus

Publications and source records attributed to V S Petrus.

At least 19 recordsLinked to original sources
PubMed1985

[Potentiation of the action of antibiotics by ultrasound].

The aim of the study was to investigate the action of ultrasound on antimicrobial drugs and to estimate the effect of antibacterial drugs and ultrasound used in combination and alone. In the first series of the experiments it was shown that under the action of ultrasound such antibiotics as benzylpenicillin, streptomycin, ampicillin, lincomycin, monomycin, rifampicin and gentamicin, and antiseptic drugs such as furacin, rivanol and iodinol did not change their antibacterial (bacteriostatic and bactericidal) properties with regard to Staphylococcus aureus and Escherichia coli. In the second series of the experiments it was shown that ultrasound potentiated by 1.7-10.8 times the antibacterial effect of the drugs. Probably, ultrasound promoted closer contacts of the drugs with the microbial cell. In the third series of the experiments it was shown that ultrasound lowered to 24.1 per cent the count of the bacterial cells capable of multiplication, while ampicillin lowered their count to 52.6 per cent. When the antibiotic and ultrasound were used in combination the count of the bacterial cells capable of multiplication was lowered to 5.2 per cent. Therefore, the combined use of the antibacterial drug and ultrasound resulted in a 4.48-fold increase of the total effect.

Anti-Bacterial Agents↗
PubMed1977

[Characteristics of bacteria of the genus Citrobacter, isolated from healthy children and children with different acute gastrointestinal diseases].

The authors examined 250 children suffering from various acute gastrointestinal diseases, and 100 healthy children. Positive cultures of bacteria belonging to the Citrobacter genus were obtained in 38% of the patients and in 20% of the healthy persons. There were revealed no cultural or biochemical differences between the strains isolated from the sick and healthy individuals. There were revealed no cultural or biochemical differences between the strains isolated from the sich and healthy persons. A total of 189 strains were identified serologically. Serological types 01, 03, 04, 08, 021, 022, the ones most frequently encountered in sick children, were absent or rarely found in the healthy. Sensitivity of the majority of the strians to the main antibiotics used in medical practice was weak; the strain isolated from the sick and healthy children failed to differ by the antibiotic sensitivity.

Acute Disease↗
PubMed1975

[Characteristics of capsular bacteria, isolated from children with acute intestinal diseases].

A study was made of 256 young children suffering from gastroenterocolitis, dyspepsia, food poisoning for the presence of conditionally pathogenic representatives of the Enterobacteriaceae family. Klebsiellae were isolated in 39.8% of the patients and in 22.3% of 67 healthy children. A study was made of morphological, cultural-biochemical properties and the antigenic structure in 308 strains of the Klebsiella denus. Capsules were detected by microscopic examination. Biochemical properties were determined after Kaufman, and some of the cultures proved to differ from the typical biochemical pattern described by this author. K-antigen was found in 185 klebsiella strains; of this number 99 strains belonged to Kl. pneumoniae and 86--to Kl. aerogenes. Fimbria were revealed in some of the Kl. pneumoniae and Kl. aerogenes strains. Bacteriocines were detected in 103 of 206 strains (by Abbot and Shennon's method).

Antigens, Bacterial↗