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Biomedical subjects

V S Sidorov

Publications and source records attributed to V S Sidorov.

At least 19 recordsLinked to original sources

[Primary double contrast study of the large intestine using citrate-sorbitol-barium suspension in the diagnosis of chronic colitis].

X-ray investigation of the colon was conducted in 292 patients with clinically diagnosed chronic colitis: standard 3-phase irrigoscopy-in 189 patients and a primary double contrast study of the colon with citrate-sorbitol-barium suspension in 103. Basing on x-ray and morphological findings, the diagnosis was confirmed in 128 patients of the 1st group (68.2%) and in 89 patients of the 2nd group (86%). The primary double contrast study of the colon was found more effective as it permitted the detection of elements of the mucosal "microcontours": transversal strips, not coinciding with haustration, focal granularity, diffuse granularity, small barium suspension "depots" or "niches", nodular granularity. It permitted the recommendation of the method for a wide clinical use.

Adult↗

[Isolation of human serum lipoproteins using a sedimentation method and the determination of their lipid composition].

A method for separation of human blood serum lipoproteins into 3 fractions (low- and high-density lipoproteins, subfractions 2 and 3) is described in detail. The method may be used to rapidly obtain information on the status of lipid metabolism in humans and animals. The results of lipid composition analysis of individual lipoprotein fractions are presented. These data were obtained in a series of experiments and EC-1052 computer-processed with the use of a COM applied program pack. Basing on the results of investigation of individual fractions' lipid composition, the authors make a conclusion on the characteristic features of each fraction, which in future may be helpful in the diagnosis of pathologic process and in detection of lipid metabolism disorders in the body.

Humans↗

[Means of improving the diagnosis of cancer of the large intestine].

Problems of perfecting diagnosis of colorectal cancers are discussed with a view to identification of follow-up groups and improvement in methods for X-ray examination and subsequent diagnostic procedures. Double-contrast enema examination should be preferred in those at high risk for cancer of the large bowel. Follow-up groups were identified on the basis of risk factors. Patients' preparation for double-contrast enema including saline and contact purgatives, residue-free diet and hydration is described. The composition of a high-contrast barium suspension is given. The method of primary double-contrast enema, the required projections and other roentgenologic technicalities, which ensure the diagnostic value of the procedure are discussed. Complex syndrome-based roentgeno-endoscopic examination programs are suggested.

Adult↗

[Analysis of the quality of clinical diagnosis from generalized findings of the pathologoanatomic service].

A statistical analysis of generalized data of the pathoanatomical service on quality of clinical diagnosis in curative-prophylactic institutions in 54 administrative territories of the RSFSR was carried out. The structure (extensive indices) and frequency (intensive indices)of erroneous clinical diagnoses referring to the most important classes of diseases were identified. As to the structure of indices and frequency of clinico-anatomic disparities the first place was occupied by oncological diseases (20.1+/-0.11 and 14.2+/-0.22%), the second--by infectious diseases (16.5+/-0.1 and 13.0+/-0.34%), the third--by diseases of the digestive system (14.6+/-0.09 and 13.0+/-0.33%), the forth--by diseases of the urogenital system (14.0+/-0.09 and 12.2+/-0.49%), the fifth--by disease of the respiratory system (12.7+/-0.09 and 10.6+/-0.24%), the sixth--by diseases of the cardiovascular system (11.1+/-0.08 and 8.0+/-0.14%). The recommendation is put forward to carry on annually a complex satistical analysis of extensive and intensive indices of erroneous clinical diagnoses demonstrating the quality of clinical diagnosis in therapeutic institutions of a given administrative territory.

Diagnostic Errors↗