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Biomedical subjects

V S Snigirev

Publications and source records attributed to V S Snigirev.

11 recordsLinked to original sources
PubMedDate not supplied

[General anesthesia, hormones and hemodynamics during the excision of tumors of the posterior cranial fossa].

The levels of tropic and peripheral hormones (ACTH, TSH, STH, T3, T4, hydrocortisone, insulin) have been assessed in 74 patients, aged 16 to 64 years, operated on for posterior cranial fossa tumors. Depending on the basic anesthesia component the patients were divided into 3 groups: patients on halothane anesthesia, patients on anesthesia with azeotropic mixture, patients on neuroleptanalgesia. Three hemodynamic variants in the course of operation and postoperative period have been established: patients with normal blood pressure, heart rate, stroke volume; patients with elevated and high blood pressure; patients with unstable hemodynamics. It has been found that general halothane and azeotropic mixture anesthesia is associated with marked changes in intraoperative endocrine function. Endocrine function is changed on the 3rd and 7th day postoperatively due to surgical brain trauma.

Adolescent↗
PubMedDate not supplied

[Status of blood coagulation and various background endocrine indices in patients with basal meningiomas during pre- and postoperative periods].

The condition of blood coagulation activity and the indices of the endocrine background were studied in patients with tumors of prevalently basal localization which caused a direct effect on the central regulating centers. Thirty patients with basal and medially located meningiomas were examined in the pre- and postoperative periods. Before the operation most patients had clinical signs of endocrine-metabolic disorders, often in the presence of an increased content of ACTH and cortisol in the blood. Blood coagulation was disturbed in the majority of patients, mainly due to increased activity of the blood coagulation system. In the postoperative period, blood coagulation activity in 24 of 30 patients was increased or showed a tendency to increase in the presence of elevated blood ACTH content while processes of fibrinolysis were inhibited, which substantiates the necessity for anticoagulant therapy when large doses of glucocorticoids are used.

Adrenocorticotropic Hormone↗
PubMedDate not supplied

[The radionuclide diagnosis of pathology of the cerebrospinal fluid tract in posttraumatic states].

Radionuclide cisternomyelography performed in 324 patients with posttraumatic injuries revealed the abnormality of the brain liquor tracts. The radiological picture of craniocerebral injury sequelae showed a great diversity of radionuclide signs, detected both morphological changes in the liquor tracts, and liquorodynamic disorders. The morphological disorders recorded by radionuclide cisternomyelography appeared as hydrocephalus, porencephalitis, arachnoidal cysts and liquorrheas. The liquorodynamic disorders recorded by this tool manifested themselves as altered liquor circulation and resorption. Radionuclide cisternomyelography provides valid data on the performance of the drainage system during operations on the liquor tracts of the brain and spine.

Adolescent↗
PubMedDate not supplied

[Internal hydrocephalus and basal liquorrhea (radionuclide data)].

The paper shows the value of radionuclide cysternomyelography in the diagnosis of internal hydrocephalus concurrent with basal liquorrhea. The authors examined 1522 patients of whom 105 were found to have the pathology, this yielded radionuclide differential diagnostic criteria for this nosological entity. They proposed new technological conditions for enhancing its diagnostic value.

Adult↗
PubMedDate not supplied

[Pathology of the cerebrospinal fluid tract after subarachnoid hemorrhages (the x-ray and radiological aspect)].

The authors examined the semiotics of hydrocephalus occurring after subarachnoidal hemorrhages (SAH) from arterial aneurysms and arteriovenous malformations to provide pathogenetic evidence for surgical or conservative hydrocephalus. The spinal fluid tract was examined in 44 patients after SAH by computed tomography and radionuclide cysternomyelography using 99mTc. Variability was found in the radiological semiotics of open internal hydrocephalus. Radiological studies revealed frequently open internal hydrocephalus in patients with arterial aneurysms and arteriovenous malformations without subarachnoidal hemorrhages. The radiological semiotics of open hydrocephalus after SAH determines both morphological changes of the spinal fluid tract and liquorodynamic disturbances.

Adult↗
PubMedDate not supplied

[The x-ray radiological semeiotics of the pain syndrome in a traumatic lesion of the brachial plexus].

X-ray radionuclide studies revealed a variety of morphological changes at the cervicothoracic levels of the spinal cord and its meninges. Despite a preganglionary injury to the brachial plexus, there was a clear-cut correlation between the level and nature of an injury on the one hand, and the severity of the pain syndrome, on the other. A more significant progression was observed in abruption of the inferior roots than in that of superior ones. The X-ray radionuclide correlations allow one to assess the nature of abnormal changes not only at the preganglionary, but postganglionary levels.

Accidents, Traffic↗
PubMedDate not supplied

[A trial of the clinical use of the Testascan computerized gamma tomograph in neurosurgical pathology].

The paper outlines the diagnostic potentialities of the first Russian multidetector Testascan gamma-tomograph. With this, three different radio pharmaceuticals (RP) were used; 99mTC-GM PAO for examining cerebral circulatory disorders, 99mTC pertechnetate for visualizing tumor foci, and 99mTC-DTPK for studying impaired cerebral liquor pathway. Regional cerebral blood supply was studied in 78 patients with arterial aneurysms and arteriovenous malformations, with stenoses and thromboses of the great arterial trunks, as well in patients with brain injury sequelae and hypophyseal, craniofascial, and cavernous sinus tumors, VIII-neurinomas, meningiomas of the pyramid of the temporal bone. Some 103 patients with various intra- and extracerebral volumetric formations are examined. The impaired cerebral liquor pathways were explored in 27 patients with pathological processes of various genesis. Experience in clinically using the Russian Testascan computer gamma-tomograph in neurosurgical care has shown its high validity in diagnosing various focal processes of tumor and nontumor genesis. Single photon emission computerized tomography (SPECT) may reveal foci of abnormal elevation or reduction of RP accumulation by showing different anatomically topographic characteristics. SPECT is the most promising in the study of cerebrovascular diseases of various genesis and in the presence of tumors at basal sites.

Brain↗