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Biomedical subjects

V Schmehl

Publications and source records attributed to V Schmehl.

7 recordsLinked to original sources
PubMed1991

[Esophageal function in chronic alcohol abuse].

1. In our patients the chronic overindulgence in alcohol led to an increased appearance of a pathological gastrooesophageal reflux. Thereby the group with normal liver findings or steatosis showed a slightly pathological, the group with alcoholic liver cirrhosis a severe pathological reflux behaviour. 2. The manometric findings in form of a decreased resting pressure in the inferior oesophageal sphincter, a slightly increased duration as well as of a decreased speed of the contraction wave were certainly insignificant in functional respect. They could not explain the pathological reflux behaviour. 3. The chronic abuse of alcohol did not lead to erosive changes of the mucous membrane in the distal oesophagus.

Adult↗
PubMed1988

[Roentgenologic documentation of findings in coloscopy].

This contribution covers the X-ray documentation of primary coloscopy findings in 29 patients. High coloscopy as a primary method of diagnosis used to have the disadvantage that when dealing with a circumscribed lesion requiring surgery, a barium enema had to be administered on order to localize it and determine its extent. The endoscopic-radiological coloscopy method described here combines primary coloscopy with a spatial visualization of the colon on an X-ray picture. It should bei applied wherever coloscopy is used as the primary method of examining the colon.

Colonic Diseases↗
PubMed1988

[Esophageal function in duodenal ulcer].

We examined 21 patients with duodenal ulcer confirmed by endoscopy for disturbances of esophageal function, using manometric techniques and long-term pH measurement. Pathological manometric findings, largely of a mild degree, were obtained in 48 per cent of the patients examined, and a pathological gastro-esophageal reflux was found in 81 per cent, with only 33 per cent suffering from reflux esophagitis as confirmed by endoscopy and/or histological examination. Although duodenal ulcer and disturbed esophageal function often appear simultaneously, a causal connection seems unlikely. Alcohol and nicotine stimulate reflux, with the degree of severity depending on the amount.

Adult↗
PubMed1988

[Esophageal function in portal hypertension before and after sclerotherapy].

An examination of esophageal function using manometric techniques and long-term pH measurement was carried out on 14 patients suffering from cirrhosis of the liver who had esophageal varices. The resting pressure in the lower esophageal sphincter was found to be slightly reduced in 50 per cent of those examined, while 100 per cent showed a slightly reduced contraction amplitude in the distal tubular esophagus which became progressively lower in the distal direction, and a pathological gastro-esophageal reflux was observed in 57 per cent. We were able to carry out a control examination on 10 of these patients after sclerosing procedure. Sclerotherapy was found to have lowered resting pressures in the lower esophageal sphincter in 80 per cent of those patients, while all of them showed a grossly impaired tubular peristalsis in the form of simultaneous, mostly repetitive contractions with a considerably lowered contraction amplitude, however it had no negative influence on gastro-esophageal reflux patterns.

Adult↗
PubMed1988

[Chronic drug-induced hepatitis caused by dihydralazine].

Two cases are described, which revealed the picture of a dihydralazine-induced chronic aggressive hepatitis bioptically. One case was laparotomized under the clinical diagnosis of obstruction jaundice, the other exhibited no symptoms and was detected by elevated transaminases only. The time of exposure was 2-3 years. After withdrawal of dihydralazine the patients recovered within 2-3 months. Elevated transaminases (more than 1 mumol) should given occasion for withdrawing the drug or for performing of liver biopsy. In a total of 6,581 liver biopsies within five years an acute dihydralazine-hepatitis was seen more frequent than a chronic one (ratio 77:2).

Aged↗
PubMed1987

[Comparison of the results of the measurement of O2 consumption with a conventional bacteriologic method for urine obtained by bladder puncture].

A method is described which utilizes the O2 consumption of aerobes and facultative aerobes from urinary tract infections for their detection. Urines obtained by puncture and the corresponding midstream urines were examined for verification. Irrespective of secondary contamination and the presence of non-causative organisms, the O2 consumption method permits the detection of a bacterial urinary tract infection within 1 h. When this method was used, a comparison between midstream urine and urine obtained by puncture showed a complete coincidence. The O2 method has shown a sensitivity of 96.9% at a specificity of almost 100% for bacterial concentrations of more than 10(5)/ml in the urine obtained by puncture.

Bacteria, Aerobic↗