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V Schmidtke

Publications and source records attributed to V Schmidtke.

2 recordsLinked to original sources

Secondary-task effects on sequence learning.

With a repeated sequence of stimuli, performance in a serial reaction-time task improves more than with a random sequence. The difference has been taken as a measure of implicit sequence learning. Implicit sequence learning is impaired when a secondary task is added to the serial RT task. In the first experiment, secondary-task effects on different types of sequences were studied to test the hypothesis that the learning of unique sequences (where each sequence element has a unique relation to the following one) is not impaired by the secondary task, while the learning of ambiguous sequences is. The sequences were random up to a certain order of sequential dependencies, where they became deterministic. Contrary to the hypothesis, secondary-task effects on the learning of unique sequences were as strong or stronger than such effects on the learning of ambiguous sequences. In the second experiment a hybrid sequence (with unique as well as ambiguous transitions) was used with different secondary tasks. A visuo-spatial and a verbal memory task did not interfere with the learning of the sequence, but interference was observed with an auditory go/no-go task in which high- and low-pitched tones were presented after each manual response and a foot pedal had to be pressed in response to high-pitched tones. Thus, interference seems to be specific to certain secondary tasks and may be related to memory processes (but most likely not to visuo-spatial and verbal memory) or to the organizations of sequences, consistent with previous suggestions.

Adolescent

Follow-up study of renal transplants by duplex Doppler and gray-scale ultrasound.

In the early postoperative period after renal transplantation 388 follow-up ultrasound examinations were performed in 77 patients. Over a period of 18 months standardized duplex indices (resistive index, pulsatility index) and gray-scale parameters (parenchyma/sinus index; medulla/cortex index) were sampled. These data were correlated retrospectively with clinical and pathological diagnoses. To delineate the individual course of duplex and gray-scale indices during different transplant diseases we created a new parameter: the MID (maximal index difference) which is a result of the difference between the highest index during the phase of renal dysfunction and the lowest index during the phase of normal renal function. This MID, calculated for duplex indices and for the parenchyma/sinus index, indicated significant differences in the behavior of renal transplants during the four main diseases: interstitial rejection, vascular rejection, acute tubular necrosis and Cyclosporine A nephrotoxicity. Using the MIDs, a table of cut-off values was established, which enables to differentiate retrospectively these four transplant complications with a sensitivity of 84% and specificity of 81%. In our opinion consequent follow-up examinations with duplex and gray-scale sonography should be performed, enabling sonography to become a helpful diagnostic instrument in the monitoring of renal transplants.

Cyclosporine