Relapse rate and low serum neuroleptic levels in schizophrenics treated with fluphenazine: another view.
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Biomedical subjects
Publications and source records attributed to V Slater.
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The vicissitudes of medical treatment are affected in large part by patient compliance. Noncompliance can be caused by a variety of psychological, somatic, and socioeconomic factors. Overcompliance would seem on the surface to be less of a problem, but it too can have serious consequences in terms of treatment success. Several psychological factors account for overcompliance. The physician's best defenses against both noncompliance and overcompliance are to listen carefully to the patient for clues to one of these impending behaviors and to establish good rapport with the patient. An individualized approach is important, and in some cases participation in organized self-help groups is of benefit.
Contradictory information exists with respect to lithium dosage in elderly patients with affective disorders. To determine the relationship between age and lithium blood levels, we studied 66 outpatients in stable condition and receiving maintenance lithium therapy. The salient question was whether the same dosage of lithium will produce similar blood levels in both old and young adults. Our results revealed no significant correlation between age and dosage. The data suggest that the dosage of lithium required to maintain a therapeutic blood level is the same regardless of age. We therefore suggest that lithium therapy be individualized according to the total clinical picture rather than chronologic age.
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This study of 561 rural North Carolina adolescents examined relationships among race, parental educational level, family structure, parental discipline, family violence exposure, and dating violence experiences. The sample was predominantly female (77%), with 40% black and 58% white. The subjects ranged in age from 15 to 20 years; 80% of the adolescents were 16-18. Dating violence experiences were assessed by a researcher-constructed instrument measuring warning signs of potential violence and actual violent experiences. The results suggested that recognition of abusive relationships is difficult, with many adolescents denying such a relationship but actually reporting numerous abusive events. Sixty percent had experienced violent acts during dating relationships; 24% reported extreme violence (episodes of rape, use of weapons). More than 20% of the adolescents reported family violence and 2.2% reported family sexual abuse. The study suggests new avenues for research in adolescent date violence, and for interventions with high risk groups.
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