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Biomedical subjects

V Sloss

Publications and source records attributed to V Sloss.

11 recordsLinked to original sources

Controlling ocular squamous cell carcinoma in Hereford cattle.

In 3 herds 737 Hereford cattle were examined for neoplastic ocular lesions at intervals ranging from 20 to 242 days. Initially all lesions greater than 3 mm diameter were treated by cryosurgery; smaller lesions were left untreated. At subsequent inspections, lesions which had increased to 5 mm diameter were treated. The prevalence of ocular lesions in the herds ranged from 8.1 to 45.7% at the commencement of the study, and from 1.5 to 8.8% after 3.5 years. In treated cattle 71% of lesions regressed after one or two treatments. Seventy-five percent of the small untreated lesions regressed. The progression of lesions and occurrence of new lesions was highest during summer and lowest during winter. It was concluded that inspection of eyes for lesions should be at intervals of 3 to 4 months, and include one during the summer. It is feasible for owners to detect and identify cattle with ocular lesions and to present for treatment those that have grown since the preceding inspection to a size nearing or exceeding 5 mm diameter.

Animals↗

The use of Clenbuterol to produce relaxation of the myometrium during caesarean operation in cattle.

The tocolytic drug Clenbuterol was clinically tested as a means of producing relaxation of the myometrium to facilitate exteriorisation of the uterus during Caesarean operation in 17 cows. When myometrial tone was found to be high during surgery, the intravenous injection of 10 ml of Clenbuterol resulted in a lowering of tone in less than 3 min allowing easy exteriorisation of the uterus. Alternative methods of myometrial relaxation are compared.

Adrenergic beta-Agonists↗

Anoxia in the bovine foetus.

Laparohysterotomies were performed, under local analgesia, on 18 plurigravid Herefore cattle and the response of their foetuses to anoxia was examined. All control and 4 of 6 foetuses subjected to 4 minutes of anoxia survived whereas all others died when the umbilical cord was clamped for 6 or 8 minutes. Death mostly occurred just before or soon after delivery, which was undertaken immediately following release of the umbilical clamp. In 2 cases, however, the calves survived for at least 2 days before being slaughtered when death appeared imminent. During the intervening period both animals failed to suck although one was able to stand temporarily following the oral administration of glucose and milk. Studies on the blood-gas and acid-base status of the foetuses while the umbilical cord was clamped revealed a decline in pH, pO2 and standard bicarbonate levels, the development of a base deficit and an increase in pCO2 and lactate levels. Clamping of the umbilical cord usually resulted in some foetal movement and the release of meconium. Clamping of the imbilical cord also caused an almost immediate fall in the pulse rate, which gradually increased after several minutes and became irregular and weak. Post-mortem examination of foetuses or calves dying from anoxia revealed haemorrhages throughout the body, these always being found on the heart, usually in the thymus and spleen, and occasionally in other sites throughout the body.

Animals↗

Elective caesarean operation in Hereford cattle.

An elective left flank Caesarean operation was performed on 56 Hereford cattle and the influence of various surgical techniques on the postoperative progress assessed. A paravertebral nerve block produced effective analgesia in all layers of the abdominal wall of all cattle. In contrast, tissue infiltration, in the form of an inverted L block, did not produce analgesia of the peritoneum and was generally only partly effective in the muscle layers of fat animals. The use of spasmolytic drug facilitated handling of the uterus. Xylazine, when given to unmanageable animals, noticeably increased uterine tone even when used in conjunction with a spasmolytic. Three animals (5.4%) died from generalised peritonitis. Peritoneal adhesions developed in 29 animals (51.8%) and minor wound dehiscence and/or suture infection occurred in 8 animals (14.1%). Postoperative subcutaneous emphysema developed in ;23 cattle (41%). The absence of sutures in the peritoneum was associated with a significant increase in the occurrence of subcutaneous emphysema. Although the prevalence of retained foetal membranes was high this did not seem to influence the postoperative progress of the animal.

Anesthesia, Obstetrical↗