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V Sreenivas

Publications and source records attributed to V Sreenivas.

29 records · Page 2Linked to original sources

An autopsy study of relationship between perinatal stomach capacity and birth weight.

BACKGROUND: Aspiration pneumonia is a common complication of overfeeding in neonates. Since overfeeding may be related to neonatal stomach capacity, it was considered worthwhile to obtain such data. AIMS: To measure the capacity of stomach obtained from fresh stillbirths and liveborn infants at autopsy and correlate the same with their birth weights. METHODS: Stomach capacity was measured at autopsy in 63 stillborn and 37 newborn infants with birth weights ranging from 500 g to 3500 g. RESULTS: Stomach capacity had a significant positive correlation with birth weight (r = 0.56, p < 0.001). A formula and a nomogram have been derived to estimate stomach capacity from birth weight. There was no significant difference in stomach capacity between liveborn and stillborn infants in any of the weight groups, except in the 1501-2000 g weight group (p < 0.001). CONCLUSIONS: Our results have provided normative data on stomach capacity across a wide birth weight range in the perinatal period.

Birth Weight↗

Some indices pertaining to the leprosy control programme in Tamil Nadu, based on data from a random sample of fourteen government control units.

From a random sample of 14 Government Leprosy Control Units in Tamil Nadu, information on the profile of the newly-diagnosed leprosy patients and some important aspects of the control programme in 1978-81 was collected when monotherapy with dapsone was the practice. Among the new patients, 55 per cent were males, 24 per cent were children, 6 per cent had lepromatous leprosy and 9 per cent had a deformity. About 65 per cent were detected by active case-finding methods and 25 per cent were voluntary referrals. Of the total diagnosed patients, only 68 per cent started treatment; further, of these, about 40 per cent collected drugs for at least 6 months in the first year of treatment. The average attendance at the clinic was 34 per cent of the due attendance. Coverage in the annual examination of family contacts was 57 per cent. During the 4 yr period, about 70 per cent of the villages had population surveys with a coverage of 75 per cent or more. The introduction of multi-drug therapy has provided a new impetus to the programme and therefore a similar study is called for to provide valuable information about the extent of improvement in completion rates and overall impact.

Adolescent↗

New manifestations of Neu-Laxova syndrome.

We report on a newborn boy with Neu-Laxova syndrome and spina bifida, bilateral cryptorchidism, and shallow orbital cavities. Association of these manifestations in Neu-Laxova syndrome is the first to be reported in the literature. This is the first report of Neu-Laxova syndrome from India.

Abnormalities, Multiple↗

A simulation approach for estimating the loss of womanyears due to cervical cancer and probability of developing cervical cancer.

Using a simulation approach, the number of womanyears that can be saved by preventing cancer of the uterine cervix was estimated. Probabilities of developing cervical cancer in the lifetime were also estimated. The number of years saved varied from 42 in the women aged between 20 and 24 years to 2 years in women aged 70 years and above. Probabilities of developing cervical cancer in the lifetime varied from 5.2% in women aged between 20 and 24 years to 0.6% in women aged 70 years and above. The results indicate that a noticeable incidence starts only after 35 years of age and about 90% of the total years can be saved by preventing the disease in women aged between 35 and 64 years.

Adult↗

Controlled, semielective, segmental resection for massive colonic hemorrhage.

An aggressive diagnostic work-up to determine the site of bleeding was employed in all 25 patients requiring transfusion of over 1,500 cc of blood for colonic hemorrhage in New Haven in 1977 and 1978. A specific bleeding site that permitted segmental colectomy was found in 23 patients (92 percent). The mortality rate was zero, reflecting the rapid improvement in survival that has occurred in the last decade among patients with massive colonic hemorrhage.

Aged↗

Signs of inflammation in children that can kill (SICK score): preliminary prospective validation of a new non-invasive measure of severity-of-illness.

BACKGROUND: Signs of Inflammation in Children that can Kill (SICK score) is a new severity-of-illness score. It uses the physical signs of the Systemic Inflammatory Response Syndrome (SIRS) and its continuum--the Multiple Organ Dysfunction Syndrome (MODS). The development of the score used multiple logistic regression model coefficients converted to integer scores that have been published earlier. AIMS: The present study was done to validate the scoring system by predicting outcomes in a fresh data set. SETTING: Intensive care unit in a tertiary referral hospital. DESIGN: Prospective. MATERIALS AND METHODS: 125 admissions to the intensive care unit were evaluated so that the SICK score and the PRISM score could be calculated. In-hospital mortality was noted. STATISTICAL ANALYSIS: Calibration (Hosmer-Lemeshow goodness of fit) and discrimination (area under the ROC curve) were used to measure performance. RESULTS: Of the 125 patients studied 23 died. The area under the ROC curve was 0.76 compared to 0.80 in the development sample. Using PRISM in the validation group, the ROC was 0.78. Calibration was excellent. CONCLUSION: The SICK score can predict severity of illness with nearly the same accuracy as the PRISM score. The SICK score can be calculated immediately on admission and can help to prioritize care for the more sick children who need urgent aggressive management. Larger studies, that includes all admissions to the hospital, will now need to be done.

Child↗