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Biomedical subjects

V Stanĕk

Publications and source records attributed to V Stanĕk.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Topography of foci of perfusion defects after myocardial infarct on standard ECG and thallium stress scintigraphy].

65 patients after previous myocardial infarction well documented by electrocardiography were investigated by 201-Tl scintigraphy after submaximal ergometry. Topographic results of the scintigraphy in three planes were compared with the location of previous infarction demonstrated by standard electrocardiography. 30% of disagreements and partial agreements in more than half the patients were caused predominantly by inability of electrocardiography to qualify a true ischaemic necrosis in the interventricular septum, by limited ability to localize exactly the site of myocardial infarction and by underestimating its size, in particular in the posterior left ventricular wall, where the lesion often extends to the lateral wall. Some principal disagreements of both methods in different findings on the anterior and posterior left ventricular walls stress the low value of standard electrocardiography for exact topographic diagnosis of the infarct site. The authors express their opinion that the size of myocardial infarction and its influence on left ventricular function measured by non-invasive methods in the acute state would be more important for the prognosis of the patient.

Adult↗
PubMed1989

A comparison of radionuclide and contrast left ventriculography and coronary angiography in patients after myocardial infarction.

61 patients after myocardial infarction were investigated by selective coronarography, contrast (LVG) and gated radionuclide ventriculography (RNV, rest and mild exercise). Left ventricular ejection fraction (LVGEF and RNVEF, resp.) and regional contractility disturbances were determined (in RNV by Fourier transform and factor analysis). A high correlation of rest LVGEF and RNVEF was found, with lower RNVEF values. A significantly lower rest RNVEF with no change during exercise was observed in comparison to 29 control persons. The ability of RNV to detect regional wall contractility impairment was nearly the same as that of LVG. RNVEF was negatively influenced by LAD obstruction and furthermore in combination with other main coronary artery jeopardy. Gated RNV is a valuable noninvasive method that could replace contrast LVG in the assessment of left ventricular function.

Adult↗
PubMed1986

M-mode echocardiography in acute pulmonary embolism.

Twenty-two patients with acute pulmonary embolism were examined by M-mode echocardiography. It was possible to examine both ventricles (with precordial approach) and the right branch of the pulmonary artery (with suprasternal approach) in all patients. With significant pulmonary embolism there occurs dilatation of the right ventricle and of the right branch of the pulmonary artery. The size of the right branch of the pulmonary artery in patients was significantly different from that of healthy volunteers. However, no significant correlation between the degree of anatomic changes (documented by echocardiography) and haemodynamics in the lesser circulation was found. Literature concerning other possibilities of echocardiography in the diagnosis of acute pulmonary embolism is reviewed. Echocardiography represents a suitable complement to diagnostic methods used for the assessment of acute states.

Acute Disease↗
PubMed1985

Clinical diagnosis of haemodynamically significant pulmonary embolism in a coronary care unit.

The study analyses 58 consecutive (1971-1981) cases with haemodynamically significant pulmonary embolism (PE) treated in a coronary unit. The diagnosis was confirmed either by pulmonary angiography or a combination of scintigraphy with haemodynamic examination, or by autopsy. In 75.8% of cases there were present predisposing factors. A combination of sudden dyspnoea with venous thrombosis or with recurrent thrombophlebitis in the anamnesis was present in 59.3% acute cor pulmonale in 1/3 of the patients. The chest X-ray showed in 83.9% of the patients one of the following signs: pulmonary infarction, oligaemia, elevation of the diaphragm, enlargement of the hili, amputation of the hili, pleural effusion. In 62.7% of the patients, PE could be diagnosed on the basis of the ECG. Most patients had elevated pulmonary artery pressure, with a worse prognosis in patients exhibiting a pressure higher than 40 mmHg. For suspecting the presence of haemodynamically significant PE, it is in most patients sufficient to rely on the anamnesis and the results of physical, ECG and X-ray examination. The diagnosis should be confirmed by scintigraphy or angiography and haemodynamic examination.

Adult↗
PubMed1984

Evaluation of the effect of nifedipine in men after myocardial infarction.

The acute effect of nifedipine (Adalat, Bayer) was evaluated in 54 men with a history of transmural myocardial infarction. Haemodynamic changes (in 20 patients) and/or changes in left ventricular radionuclide ejection fraction (LVREF) (41 patients) were studied. 20 to 30 min after sublingual administration of 1 Adalat capsule (10 mg nifedipine) a decrease in arterial pressure and systemic resistance, and an increase in heart rate and cardiac output were observed already at rest. During exercise (50 W) there moreover occurred a decrease in pulmonary artery pressure and in arterial oxygen tension. LVREF was pathologically reduced already at rest, and in most patients exercise led to its further decrease. LVEF increased after Adalat administration only during exercise. In men with a history of myocardial infarction without clinical manifestations of heart failure, Adalat acted predominantly as a peripheral vasodilator; a negative inotropic effect was not demonstrable. The decrease in arterial oxygen tension, observed during exercise, was not clinically important.

Adult↗
PubMed1983

Equilibrium radionuclide ventriculography in men after transmural myocardial infarction.

Using equilibrium radionuclide ventriculography, the authors investigated left ventricular ejection fraction in 10 healthy men and in 57 men who had undergone their first transmural myocardial infarction (MI) 4 to 7 months earlier, were below 65 years of age and did not present signs of heart failure at the time of examination. Resting ejection fraction in healthy men amounted to 63 +/- 5%, in patients with uncomplicated MI to 54 +/- 7%, and in patients with clinical manifestations of heart failure in the acute phase to 37 +/- 8%. Patients with anteroseptal MI showed a negative correlation between the ejection fraction, on the one hand, and the sum of Q wave voltages in the precordial ECG map and the maximum value of serum creatine kinase in the acute phase of MI, on the other hand. The ejection fraction correlated with the degree of pulmonary hypertension during exercise. At work load of 50 W the ejection fraction measured in 31 patients was not significantly different shortly before discharge from hospital and 6 months after the onset of MI.

Adult↗