The validity of gammacamera scintigraphy in the diagnosis of renal allograft rejection.
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Biomedical subjects
Publications and source records attributed to V Svendsen.
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Analysis of 156 first cadaver-kidney transplants performed in one transplantation center revealed a better graft survival in the group of transfused patients compared to the non-transfused patients. The degree of statistical significance between the groups improved with increasing number of pre-transplant blood transfusions. Pregnancy had no influence on graft survival. As could be expected the frequency of lymphocytotoxic antibodies before transplantation increased with increasing number of blood transfusions. However, lymphocytotoxic antibodies seemed not to influence graft survival.
The symptoms and diagnosis of perirenal lymphocele following kidney transplantation are discussed. A case demonstrated by means of i.v. urography and gamma camera scintigraphy is reported. The value of the last mentioned method is stressed.
A case of mediastinal lymphangiomyoma with tubules covered with epithelium is reported. The epithelium of these tubules is morphologically identical to that of the bronchi. It is the first time that epithelial, presumably pulmonary, elements have been described in an extrapulmonary lymphangiomyoma. It is concluded that the present case of mediastinal lymphangiomyoma suggests a hamartomatous malformation. Whether this applies in general to lymphangiomyomatosis still remains a matter of discussion.
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Gammacamera scintigraphy studies in three patients with urinary extravasation following renal transplantation are presented. Images were obtained using 131I-orthoiodohippurate. Urinary leakage were detected in each case. The diagnosis were in all three cases confirmed at surgery.
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38 diabetic patients in dialysis or after renal transplantation have retrospectively been studied to see if some of the clinical observations could be of prognostic value. The results show that cardial ectasia is correlated to a significant higher mortality, whereas the degree of diabetic retinopathy and the duration of diabetes both seem to be without prognostic importance.
A 7-year material is presented comprising 38 diabetic nephropathy patients who were treated by dialysis and transplantation. The cumulative patient survival rate after one year is 39%. The survival rate of the transplanted diabetic patient is poorer than that of the transplanted non-diabetic patient. However, no difference is to be found between the graft survival rates of the two patient groups. Forty-seven percent of the patients died from cardiovascular causes and 43% from infectious complications.
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