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Biomedical subjects

V Szabó

Publications and source records attributed to V Szabó.

At least 19 recordsLinked to original sources

Apoptosis in various organs of preterm infants: histopathologic study of lung, kidney, liver, and brain of ventilated infants.

Apoptosis, the well-characterized form of active programmed cell death, is a physiologic phenomenon in embryonal and fetal life in developing organs. Severe hypoxia, which occurs in most preterm infants, also leads to cell death, which may be necrotic or apoptotic. The aim of our study was to examine the incidence of apoptosis in various organs (such as lung, kidney, and brain) of preterm infants who suffered from clinically proven respiratory distress causing infantile respiratory distress syndrome (IRDS), cardiac failure, and periventricular leukomalacia (PVL). Twenty-four autopsy cases were studied histologically to detect the apoptotic ratio, which was performed on the basis of hematoxylin and eosin staining and validated by terminal deoxynucleotidyl transferase-mediated nick end-labeling (TUNEL) reaction. Elevated apoptotic ratio was found in stages II, III, and IV of bronchopulmonary dysplasia (BPD) among alveolar and bronchiolar cells. The apoptotic activity was very low in stage I of BPD. High apoptotic ratio was detected in hypoxic injuries of the central nervous system (CNS) of preterm infants. Features of apoptosis were present in proximal and excreting tubules of the kidney. Significant elevation of apoptotic activity may play a role in the development of BPD, ischemic brain lesions, and renal failure.

Apoptosis↗

[Botulism in infancy].

According to international references the publication ascertains the etiologic role of neurotoxin producing Clostridial spp., other than C. botulinum in Infant botulism. Authors report on the first Hungarian case of Infant botulism. The organism isolated -- C. barati -- is responsible only for a small proportion of published cases. Authors point out the conjunction of Infantile botulism and crib death.

Age Factors↗

Ultrastructural changes in the nerve elements in Crohn's disease.

Electron microscopic investigations were carried out to study the nerve elements in the wall of the small intestine in Crohn's disease, comparing it with the control. In the ileum of Crohn's disease only a few synapses were found. The number of nerve terminals were decreased, as well as that of the vesicle population in the remaining nerve terminals. Some of the nerve processes were observed in degeneration. The number of the lysosomes in the nerve cell bodies increased. Inflammatory cells as lymphocytes, plasma cells, mast cells were noted in the tola submucosa and in the mucous membrane, their number was also increased. It is suggested that the immunological effector cells and their products could be responsible for changing the neuronal elements.

Adult↗

Radical nephrectomy through total median laparotomy.

Twenty-two carcinoma patients aged less than 65 years were subjected to radical nephrectomy through total median laparotomy. This type of approach provides excellent access to both essential operation phases: vessel management and lymphadenectomy. Postoperative abdominal complications and hernia have not been encountered.

Adult↗

Ten years of diagnostic ultrasound in renal disease.

Observations with diagnostic ultrasound in renal disease over a 10-year period are reviewed. The advantages of diagnostic methods involving the least possible discomfort to the patient are emphasized. Ultrasonography is regarded as a reliable non-invasive method for the diagnostic differentiation between renal tumours and cysts. It was used by the authors for this purpose in 740 cases. Renal tumours were found by this method in 622, and renal cysts in 118 cases. Of the 740 patients, 726 underwent surgery. The preoperative ultrasonic diagnosis of renal tumour proved to be correct in 91.8 per cent, that of renal cyst in 88.9 per cent of the respective surgical cases. Ultrasonography also lends itself to the follow-up of polycystic disease of the kidney, being suited for its early diagnosis, as well as to its identification in the stage of renal failure when the traditional diagnostic methods are no longer practicable.

Diagnosis, Differential↗

[Hemostasis in transvesical prostatectomy with a modified U-shaped needle].

In transvesical prostatectomy haemostasis was achieved by the application of a modified U-shaped needle. The method was applied in 34 patients. It is suggested that the method can advantageously be applied when bleeding starts not from the loge-edge, but from the stump of the urethra or from the base of the loge. The bladder was closed by introduction of a balloon catheter and an epicystomic drain. Though the new method ensures additional advantages, it does not solve all the problems arising in connection with prostatectomies.

Aged↗

Ultrasonic measurement of residual urine: a method requiring no catheter.

Residual urine was measured with the two-dimensional and the gray-scale equipments (Kretz-Technik) in 26 cases each. The results were checked by catheterization. The difference between the ultrasonographic and the catheter values was 20 to 40 ml for the two-dimensional, but only 5 to 10 ml for the gray-scale apparatus. Ultrasonography is regarded as a reliable and entirely harmless procedure, suited for the measurement of residual urine.

Aged↗

Diagnostic ultrasound in urology.

Diagnostic ultrasound has been used over the last eight years for the demonstration of various space-occupying lesions of the urogenital tract, for the estimation of the prostate size and for the identification of intrascrotal processes and tumours. 918 patients were studied by this method. In 595 (87.3 per cent) of the 682 surgical cases in this series ultrasonic diagnosis was confirmed by the surgical finding. False-positive and false-negative results totalled 17.7 per cent. The method is particularly suited for the differential diagnosis of renal cysts from tumours without the need for other procedures involving discomfort to the patients. This procedure, which is free from any iatrogenic hazard, provides accurate information on the size and structure of space-occupying lesions.

Diagnosis, Differential↗

[Experiences with ultrasound in the diagnosis of acoustically homogeneous resistances].

For the differentiation of acoustically homogeneous resistances the ultrasound method was used in 562 cases. In the present paper is reported on the possibilities in the differential diagnostics of renal cyst and cyst-like formations given by the echo method. The new diagnostic method gives an essential help for making the exact diagnosis, taking simultaneously into consideration the findings of the traditional examination methods.

Diagnosis, Differential↗

Ultrasonography in the differential diagnosis of hydrocele.

In addition to the conventional examination methods, ultrasonography was applied in the diagnostics of testicular lesions in 18 cases. This harmless method differentiating hydrocele from testicular tumour and inguinal hernia is recommended.

Diagnosis, Differential↗