Letter: Serum complement in acute viral hepatitis.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to V T Babeş.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The sensitivity of seven commercial diagnostic kits for HBsAg detection was compared using the positive controls of the kits and a series of positive serum samples. No significant differences of sensitivity were noted between the kits, but there were some in the total reaction time and the facility of execution.
Explore the source record for details and available documents.
Partial elimination of proteins from HBsAg-positive sera was realised by raising the temperature and simultaneously lowering the pH. Products with a convenient level of purity (2.2 mg of proteins per ml) were obtained as well as a good recovery rate of the HBsAgs (8-24%).
Studies were conducted on inverse passive haemagglutination to work out more sensitive methods for the detection of serological markers of the hepatitis B virus (HBV). IgG were coupled to human red blood corpuscles (RBC) and some parameters of the RBC sensitization, to the coupling and of the test itself were investigated.
Explore the source record for details and available documents.
Some pathogenic features of viral hepatitis (VH) are analysed on the ground of literature data and personal results. Correlations concerning blood group distribution in the case of apparently asymptomatic HBsAg carriage and of acute and chronic VH, as well as correlations with individual characteristics such as age and sex a.o., are presented. The possibility that other genetic and epigenetic factors may help to a better knowledge of VH pathogeny is discussed.
The anti-HBc response was investigated by immunofluorescence in the sera of 109 asymptomatic HBsAg carriers. The results suggest the presence of at least two antigenic HBcAg determinants, possibly correlated with the replication phase. The subjects with intensive anti-HBc response showed immunological alterations consistent with the presence of active liver lesions and of hepatocellular membrane injury.