[Neurophysiological indices of voluntary and involuntary visual attention in humans].
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Biomedical subjects
Publications and source records attributed to V T Shuvaev.
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The aim of the study was to reveal a probable structural-functional basis of emotional self-regulation processes within the framework of cortex--basal ganglia interaction using on-line computer analysis of the EEG. The tested subjects were unable to overcome the emotional stress increasing in the process of decision making under conditions of high responsibility for the results of task solving. Striving to hold their social positions these subjects created a stable psychological set to keep their high responsibility and resist the relaxation tendency. Such a set facilitated the acceptance of the task for volitional effort to resist fear controlled by a biofeedback displayed in skin galvanic reaction.
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Chimpanzees with the help of reconstruction and the "step-by-step" analysis of a figure--sample can plan a circuit of actions, forming an image of an end result. Ability to such actions proves at them an opportunity of cogitative operations, allowing to collect multielement figures on a sample. Generalization of concrete operations with concrete elements creates the precondition for the generalized understanding of a principle of actions--knowledge--in general to collect separate elements in complex designs. In it the powerful conceptual potential chimpanzees is covered. It allows to use chimpanzees as model preverbal a level of thinking.
A method of construction of crossintervalograms for electroencephalograms is proposed. Particular points or EEG fragments of particular shape are used as time-locked events, and the intervals between these reference points are analyzed. The method is theoretically substantiated. Examples of crossintervalograms constructed for EEG extrema and derivative EEGextrema are given. The information validity of these crossintervalograms is demonstrated and their features are indicated. Comparison crossintervalograms with crosscorrelograms is performed. The possibilities of further development and applications of a method are specified. It is suggested that the method will be useful for investigation of operative interaction of brain subsystems.
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The influence of stimulation of the amygdala nuclei complex on the orbital cortex neurones during the formation and realization of the alimentary conditioned reflex was studied in chronic experiments on three dogs. In the course of alimentary conditioning, a qualitative change of the histograms of distribution of interimpulse intervals (III) took place. Other parameters of spike activity, also underwent changes: the mean frequency of discharges and the degree of regularity of the spike flow. Single stimulation of the amygdala decreased the mean frequency of discharges of the orbital cortex neurones, diminished the secretory conditioned reflex, reduced the regularity of the spike flow and qualitatively changed the III distribution histogram. An attempt has been made to explain the mechanism of action of the amygdala nuclei stimulation on the conditioned reaction.
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Influence of cholinergic activation of dorsal (caudo-putamen) and ventral (accumbens) striatum on active avoidance learning was studied in chronic experiments in Sprague-Dawley male rats. The results obtained on the same behavioural model testify to specific roles of dorsal and ventral cholinergic systems in the control of motor behaviour. Single carbacholine microinjection into the right Accumbens increased the level of correct responses on the first and subsequent learning days. Similar microinjection into the left accumbens on the first training day improved the level of correct responses on the second and the third learning days. Microinjections into the dorsal striatum did not change active avoidance learning in T maze. Changes in locomotor activity of the animals of different experimental groups were principally of the same nature, i.e., the level of locomotor activity in the open field decreased from trial to trial in all the groups. Carbacholine microinjection did not change spontaneous locomotion in rats. However, there were variations in modifications of locomotor activity induced by microinjections into accumbens depending on localization of the cannula. Injection into the lateral accumbens induced the most pronounced changes. This fact testifies to the functional heterogeneity of this small nucleus.
Discussion of the cortical-subcortical interactions in organization of the behavioral reaction of various biological significance. Analysis of vast original experimental data on the morphology of the amygdala-caudate relations, on the neuron reconstructions in the cortical-subcortical systems under the positive and inhibitory conditioned reflexes, on the role of individual nuclei of the amygdaloid body in the trophic and defensive reactions, in organization of internal inhibition.