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Biomedical subjects

V Tomić

Publications and source records attributed to V Tomić.

16 recordsLinked to original sources
PubMed1995

[The beginnings of otorhinolaryngology in Bosnia and Herzegovina and its development in Sarajevo].

The first ENT Department in Bosnia and Herzegovina was established in Sarajevo by Dr. Zarko Prastalo in 1923, as a part of the Surgery Clinic, with 10 beds. The next year (1924) ENT got its own operation theatre, 30 beds more and a new localization. In that period there was only one ENT specialist, Dr. Zarko Prastalo. Three years after some new doctors started the specialization in ENT. By the year 1946 the ENT Department became a University clinic with 7 doctors on duty, the Clinic became an educational centre. To the year 1992, 112 ENT specialists were educated in the ENT Clinic in Sarajevo. Later in time, after Dr. Zarko Prastalo, Dr. Ivo Herlinger, Dr. Josip Gerc and Dr. Emilija Bac became known ENT specialists. The new scientific and operation techniques came to the ENT Clinic, the first chelognapalato schisis was in 1936, done by Dr. Josip Gerc. The first ear operation using operation microscope and microinstruments was performed in 1962, while the first laryngo-micro-operation in 1971. Since 1965 th worked with the Maxilofacial Surgery, together, but in 1972 they moved to the stomatologic Clinic, With the development of the clinic, 10 our patient departments (ambulances) were established in Sarajevo. As for now, during the war, there are 101 beds, 13 ENT specialists. Dr. Sejo Sebić was killed in 1992 by the aggressor.

Bosnia and Herzegovina↗
PubMed1994

[Plasmapheresis in clinical practice].

Plasmapheresis is an immunomodulatory procedure with immunosuppressive effect. Plasmapheresis involves taking blood, separating off the plasma and returning the red cell-enriched fraction to the patient. In plasmapheresis improvement is due to the removal of mediators of tissue damage. Therapeutic plasmapheresis has been used in many diseases in which immunological mechanisms are proved. It has been noted that there may be a "rebound" in the level of antibodies and immune complexes after plasmapheresis, perhaps due to elimination of feedback suppressor mechanisms. For that reason, plasmapheresis is only effective when used as part of an immunosuppressive regimen which also includes steroids and/or cytotoxic agents.

Humans↗
PubMed1986

Morphological characteristics of the gyrus dentatus in some animal species and in man.

Comparative anatomical investigations have been carried out on the gyrus dentatus of rat, fox, cattle, domestic pig, monkey (Cercopithecus sabeus) and man. After removal of the brain stem and scaling off the brain substance from the medial aspect towards the lateral aspect, the gyrus dentatus was preserved and its relation with regard to the hippocampus, the fimbria hippocampi and the gyrus parahippocampalis was studied. A rat's gyrus dentatus occupies a rather wide zone on the medial aspect of the brain. Its surface is almost flat with very poor denticulations, and below the splenium corporis callosi it forms the tuberculum gyri dentati which is wider than the splenium. In the cat somewhat better pronounced denticulations were observed, and the gyrus dentatus was directed from the rostral aspect towards the dorsal and the lateral, and before reaching the splenium corporis callosi it changed its course towards the medial aspect and passed into the tuberculum gyri dentati. The cattle's gyrus dentatus is rather wide and macroscopically without a sharp definition from the hippocampus. Domestic pig's denticulations are better pronounced particularly towards the gyrus parahippocampalis. The gyrus dentatus of the monkey is well retracted into the fissura hippocampi and below the splenium corporis callosi the tuberculum gyri dentati is barely visible. The authors found the most developed gyrus dentatus in man, but here, the tuberculum gyri dentati was missing.

Animals↗
PubMed1976

[Injuries of the thigh bone with a destruction of the neuro-vascular bundle].

From 1969 to 1971 the authors treated 1360 injured patients, eight of which suffered serious injuries of the thigh; fractured femur complicated by a severed Femoral Popliteal Artery, and lesions of the Sciatic Nerve. Six patients were injured at work, one in an automobile accident, and one was a gunshot victim. In approximately 1000 fractures one is complicated by an injured neurovascular bundle. The clinical picture of such a case is characteristic. The arteriograph is used only to locate the lesion. Reconstruction of the artery must be accomplished some eight to twelve hours following the injury. In all of the authors' cases, this was done one to eight hours following the trauma. After twelve hours, ischemic necrosis of the soft tissue (musculature) sets in requiring amputation. The remaining segment of the damaged artery is usually resected. In one case, a segment 8 cm. long was removed. Following the termino-terminal anastomosis, the injured extremity was placed in a flexed position whlich alleviated the tension on the sutures. The result of vein autographs are worse than those of the termino-terminal anastomoses. Thrombosis later begins to restrict blood flow through the reconstructed artery, but by this time, adequate collateral circulation has been established. The limb has thus been saved. Heparin is administrated immediately before and during the operation in a dosage of 5000 units per 500 ml. of physiological solution. Postoperatively, it is not used as it acts on the fibrin thrombi, and not on the thrombocyte thrombi which are formed postoperatively in the areas where the tunica intima has been damaged. Heparin is indicated in the prophylaxis of venous thrombosis. In these cases in which the femur was fractured, the question asked is whether to perform the osteosynthesis and anastomosis simultaneously, or to perform the former at a later time. The authors chose both methods for various reasons. Only a few cases permitted the authors to decide which approach would be better. Usually they performed a temporary fixation of the bone with Rusch's Pin, and sutured the artery. Four months later, a compressive osteosynthesis using an L-plate, was performed. In four cases, the Sciatic Nerve was injured, which, according to the circumstances was sutured either immediately, or 3 to 4 weeks later. In 3 patients, good functional results were obtained. Three cases resulted in a contracture of the knee, two of which also had residual Sciatic Paresis. One case resulted in permanent venous stasis (edema of the legs, and two cases results in amputation.

Adult↗
PubMedDate not supplied

[Epithelial cells in bronchial asthma].

The paper deals with the current data on the morphologic and functional damages to the epithelium in asthma. Structure of the normal airway epithelium is briefly described. Damage to the epithelium disrupts the barrier to the external environment, and may result in changes in mucous secretion, and mucociliary clearance; induce bronchoconstriction; promote chemotaxis of inflammatory cells. Epithelial cells can present antigens to T-lymphocytes. Epithelium is both target and effector in asthma. Hypothesis that eosinophils contribute to the damage of the epithelium gained increasing recognition.

Asthma↗