Multi-organ protection and the kidney. From nephroprotection, cardioprotection, neuroprotection to multi-organ protection.
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Brain Diseases↗
Biomedical subjects
V Trandafirescu
Publications and source records attributed to V Trandafirescu.
[Immunofluorescence in various nephropathies; observations on 62 cases].
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Adolescent↗
[Evolution of post-vaccination anti-smallpox immunity in different age groups demonstrated by the titer of agglutination-inhibiting antibodies].
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Adolescent↗
Trichinous nephropathy.
Lesions of glomerular nephropathy were found in 5 cases of acute trichinosis, characterized by a low proteinuria and hematuria as well as by moderate deficit of the renal function. Renal biopsy revealed lesions of proliferative glomerulitis, while immunofluorescence examination showed granular deposits of IgG and beta1-C-globulin on basement membranes. Serum complement was reduced. These observations suggest an immunological mechanism in the development of the glomerular nephropathy during acute trichinosis.
Acute Disease↗
Immunologic investigation in cardiomyopathies.
A group of 6 patients with congestive cardiomyopathy were investigated from the immunologic pint of view. Changes of serum immunoglobulins with increase of IgA and IgM were observed in all the patients. The immunofluorescence test in myocardial fragments, taken by transparietal biopsy from the six patients, confirmed the presence of IgA and IgG in two cases. A pathogenic immunologic mechanism is discussed in cardiomyopathies and especially in the alcoholic one.
Adult↗
Some sex- and age-dependent correlations in acute viral hepatitis.
HBsAg was found to be present in 28.7% of 1980 sera from acute viral hepatitis (AVH) patients tested by immunodiffusion and counterimmunoelectrophoresis. The incidence of HBsAg-positive AVH cases was lower in female subjects aged 10-19 years. The follow up of SGPT, bilirubinemia and thymol turbidity kinetics in 473 of the patients revealed some HBsAg-dependent differences. Such differences oscillated more markedly in adults than in children and were less obvious in women. The possible involvement of certain individual factors in the determinism of hepatitis B virus infection and of its further evolution is suggested.
Adolescent↗