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V Usha Rani

Publications and source records attributed to V Usha Rani.

4 recordsLinked to original sources
PubMed1985

Absorption studies after massive small bowel resection and antiperistaltic colon interposition in rhesus monkeys.

An experimental model of massive (80%) small bowel resection and antiperistaltic colon interposition in between the remnant jejunum and ileum was created in rhesus monkeys. The gastrointestinal functions were assessed preoperatively and at different periods after the operation. Progressive increase in the transit time and enhanced absorption of D-xylose and vitamin B12 was observed in these animals. The transit time marginally increased till three months postoperatively, and a significant increase was observed later (4-12 months) in the colon autografted monkeys. After three months, the D-xylose absorption in the colon interpositioned animals was nearly equal to that of normal monkeys. There was no significant difference in the vitamin B12 absorption in the normal and operated animals up to three months, but a significant rise was observed in the latter group after this period. The fecal fat excretion was 33-44% initially, and it gradually decreased to near normal values after nine months. The antiperistaltic colon interposition was effective in improving the early postoperative survival in animals after massive small bowel resection and enhanced the bowel absorption considerably.

Animals↗
PubMed1984

Intestinal adaptation to zinc absorption following massive small bowel resection and colon interposition in rhesus monkeys.

The intestinal uptake of zinc was studied in Rhesus monkeys, after 80% small bowel resection and colon interposition in between the remnant jejunum and the ileum. The hair and serum zinc levels decreased in the early postoperative period and gradually attained normal values after three months postoperatively. A significant increase in the zinc uptake was observed in vitro, in the remnant jejunum, ileum and the grafted colon, both in six months and one year old operated monkeys, suggesting a compensatory intestinal adaptation for zinc absorption after massive small bowel resection and antiperistaltic colon interposition.

Animals↗
PubMed1984

Absorption and urinary excretion of oxalates following massive small bowel resection and colon interposition in rhesus monkeys.

The pattern of oxalate uptake in various segments of the bowel has been studied after 80% small bowel resection and antiperistaltic colon interposition in Rhesus monkeys. The levels of urinary oxalate excretion were significantly raised in the immediate postoperative period, with progressive reduction at six and 12 months. None of the animals developed renal calculi. The possible benefit of the colon interposition after massive small bowel resection, in the prevention of hyperoxaluria and urolithiasis is suggested. Improvement in the fat malabsorption, formation of insoluble calcium oxalate in the bowel lumen, leading to reduced net intestinal absorption of oxalates is the possible mechanism.

Animals↗