PubMed Health⌕ Search

Biomedical subjects

V V Alferov

Publications and source records attributed to V V Alferov.

4 recordsLinked to original sources
PubMedDate not supplied

[The dorsal hippocampus injury influences chronobiological effects of depressants and antidepressants in rats].

The administration of depressant reserpine and antidepressant imipramine in rats is manifested by opposite trends in the chronobiological aspect of behavior. Reserpine disorganizes the circadian locomotion rhythm and increases the rhythmological index of depression in the forced swim test. In contrast, imipramine increases the circadian rhythm contrast and decreases the index of depression. A bilateral lesion of the dorsal hippocampus attenuates both pharmacological effects, but the general trend has an antidepressant character: the effect of reserpine decreases, while the effect of imipramine increases. It is suggested that hippocampus probably plays an important role in the origin of depression and related chronobiological manifestations.

Animals↗
PubMedDate not supplied

[Selection methods of nodule bacteria].

The aim of selecting nodule bacteria is to obtain stable and genetically pure strains with elevated effectiveness in the conditions of symbiosis with bean plants, sufficient viability and competing ability, which would survive in soil for a long time. The following methods have been suggested to solve this task: selection by plants using mutagenic factors; genetic markers; production of genetically homogeneous material; determination of the degree of persistance effectiveness in mutants.

Bacteriological Techniques↗