PubMed Health⌕ Search

Biomedical subjects

V V Andrianov

Publications and source records attributed to V V Andrianov.

At least 19 recordsLinked to original sources
PubMed2003

Membranotropic effects of antibodies to S100 protein in ultralow doses.

Two types of neurons exhibiting various reactions to application of antibodies against S100 protein in the washing solution were revealed in the nervous system of Helix lucorum snails. After treatment with antibodies against S100 protein the frequency of action potential generation decreased in spontaneously active B1, B3, B17, and PPa6 cells, but increased in B4 and B6 cells. The effect of antibodies against S100 was less pronounced in the solution of potentiated antibodies against this protein. After pre-exposure of ganglia in the solution of potentiated water the effect of antibodies against S100 protein decreased to a lesser extent. No significant changes were revealed in the membrane resting potential of cells. Combination treatment with antibodies and potentiated antibodies against S100 protein increased the threshold of action potential generation in B1 and B17 cells. Our results indicate that potentiated antibodies against S100 protein specifically modulate the activity of nerve cells.

Action Potentials↗
PubMed2002

[Electrophysiological study of 5,6-dihydroxytryptamine effect on defensive reflex conditioning in the snail].

The role of serotonin in expression of membrane properties of identified neurons was studied during defensive reflex conditioning using the neurotoxic analogue of serotonin 5,6-dihydroxytryptamine (5,6-DHT). The defensive reflex conditioning in snails was destroyed on the second day after second injection of 5,6-DHT. Through the 1st weeks after second injection of 5,6-DHT the snails were learned but worse than snails after injection of saline solution. This result shows the recovery of snail's learning ability within 2 weeks after the second injection of 5,6-DHT. It was found that injection of 5,6-DHT prevented the decrease of membrane and threshold potentials of command neurons during defensive reflex conditioning as compared with the snails injected with 5,6-DHT without learning.

5,6-Dihydroxytryptamine↗
PubMed2002

[Time course of changes in cardiac rhythms in successful and unsuccessful solution of visual and motor tasks under the conditions of binocular and monocular visions].

The P. K. Anokhin theory of the general functional system considers integral behaviour as realization of processes aimed at reaching a useful result. Electrograms were recorded in students who were solving visual and motor puzzle tasks. Their results were estimated. There were two groups of subjects: 1) those with normal binocular vision and 2) those with monocular vision. Some specific features were found in cardiac rhythm power in each group. The findings suggest that there are relationships between the results of task solution, the type of visual perception, and heart rate parameters.

Adult↗
PubMed1996

[Polymorphism of virus-like particles of retrotransposons in Drosophila and yeast cells].

Data on the molecular arrangement of viruslike particles (VLPs) of yeast and Drosophila retrotransposons are presented. Two methods for identifying VLPs from specific retrotransposon families have been offered. The first method is based on VLPs fractionation by electrophoresis in agarose gel under strictly controlled conditions. VLPs of the Drosophila melanogaster retrotransposon families copia and gypsy and D. virilis retrotransposon Tv1 were identified by this method. The method based on heterologous induction of retrotransposons in cells of the mutant spt3 strain of Saccharomyces cerevisiae was used to identify VLPs of yeast retrotransposon Tyl and D. melanogaster gypsy retrotransposon.

Animals↗
PubMed1985

[Effect of the enzyme plasmin on blood coagulation in fish].

The influence of plasmin on blood coagulation in fishes has been studied. The plasmin administration in dose 250 conditional units has been shown to evoke hypercoagulation already on the 5th minute after injection. This defence reaction on the plasmin excess in blood flow was excluded by the preliminary administration of alpha- as well as beta-adrenoblocators. Subtle differentiation of adrenoreceptors is supposed to be absent in fishes, nevertheless they play a definite role in regulation of hemostasis system.

Adrenergic alpha-Antagonists↗
PubMedDate not supplied

The interaction of mediators with the processes of protein synthesis in neurons of the visual cortex in the goal-directed behavior of cats.

The chemical sensitivity of neurons of the visual area of the cerebral cortex of cats at sequential stages of food-procuring instrumental behavior, formed under the conditions of intraventricular administration of a protein synthesis blocker, cycloheximide, was investigated in the present study. It was demonstrated that in animals with cycloheximide there is a low level of chemical sensitivity of cortical neurons to microiontophoretically applied solutions of acetylcholine and norepinephrine. As compared with intact animals, in the animals with cycloheximide the number of neurons reacting with a change in impulse activity at the stages of instrumental behavior and the number of areactive cells did not depend on the nature of the applied neuromediator.

Acetylcholine↗