[A rare complication of tropical malaria].
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Biomedical subjects
Publications and source records attributed to V V Bogdanov.
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Electrophoretic analysis of histones bound to DNA and remaining free in the mixtures of DNA with the total histone of chromatin in a medium of physiological ionic strength has shown that even the minimal weight excess of the total histone with reference to DNA (1.1:1) leads to the formation of nucleohistone impoverished in HI fraction because of histone competition for DNA. Within the histone/DNA ratio equal to 1.4, H3, H4, H2A and H2B are bound to DNA without competition, i.e. at a ratio in which they are added to DNA. Provided the histone/DNA ratio is higher in the mixture, there form nucleohistones enriched with H3 and H4 fractions. The role of histone competition for DNA in eu- and heterochromatin assembly is discussed.
The antifungal activity of terrilitine, an enzymatic preparation of microbial origin and its effect on the activity of antifungal polyenic antibiotics and griseofulvine were studied in vitro. It was found with the method of serial dilutions in Sabourand's liquid medium that terrilitine was active against C. albicans and certain dermatophytes. In combination with amphotericin B, amphoglucamine, mycoheptine, levorin, nystatin or griseofulvin it increased the activity of these antibiotics 2-16 times.
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