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Biomedical subjects

V V Chernin

Publications and source records attributed to V V Chernin.

At least 19 recordsLinked to original sources
PubMed1992

[Chronic gastritis from the aspect of a thrombohemorrhagic syndrome].

As many as 148 patients were examined to demonstrate that chronic gastritis (CG) runs its course in the presence of marked changes in microcirculation and hemostasis which go into the framework of the chronic recurrent thrombohemorrhagic syndrome. The manifestations of the latter one were more appreciable in a dramatic exacerbation of the disease, erosive gastritis, diffuse atrophy of the mucous membrane and secretory insufficiency of the stomach, and disease standing over 10 years. The disorders indicated are involved into the pathogenesis of CG and promote the development of morphofunctional alterations in the gastric mucosa.

Adult↗
PubMed1991

[Clinico-pathogenetic aspects of peptic ulcer therapy].

Peptic ulcer therapy should be combined and take into consideration possible risk factors and the clinicopathogenetic aspects of the disease. The first stage involves the treatment of a relapse. It is to be carried out at hospital and to include protective regimen, diet, and agents that normalize disorders of nervous regulation, of secretory and motor functions of the stomach, endocrine shifts, drugs that relieve microcirculatory disorders and inflammatory phenomena, contributing to ulcer healing. The second stage involves reinforcement of the treatment results after the patients' discharge from hospital. The third stage involves carrying out of antirelapse measures. Such a principle of the patients' management enables reduction of the time of their stay at hospital by 6.2 days, increase of the percentage of ulcer healing from 76 to 94, reduction of the number of relapses by 2.5 times, decrease of the temporary disability by 3.4 times, and elimination of the disease complications.

Humans↗
PubMed1990

[Peptic ulcer].

Explore the source record for details and available documents.

Campylobacter↗
PubMed1988

[Use of histaglobulin in the complex treatment of exacerbations of chronic gastritis].

The effect of common multimodality therapy, histaglobulin course therapy was studied in 55 patients with exacerbation of chronic atrophic gastritis with secretory insufficiency and absolute hypohistaminemia. Histaglobulin enhanced the elimination of the pain syndrome and dyspeptic disorders, reduced the period of treatment in hospital, promoted the disappearance of acute phase changes in gastric mucosa, stimulated secretory and motor stomach function, and normalized histamine metabolism in the body.

Adult↗
PubMed1987

[Status of microcirculation in patients with chronic gastritis and its relation to morphofunctional changes in the stomach].

Studies on 74 patients with chronic gastritis showed that the disease was accompanied by disorders of the microcirculatory bed of the bulbar conjunctiva characterized by the appearance of perivascular edema, inhomogeneity of the vascular caliber and coiling, change of arteriolovenular ratios, the formation of vascular glomerules, neglected zones, intravascular aggregation of erythrocytes and microthromboses. These changes were combined with disorders of the end blood flow of the gastric mucosa detected in its specimens. A degree of the above disorders depended on the expression of exacerbation and period of disease, peculiarities of lesion of the gastric mucosa, secretory and motor functions of the stomach.

Adolescent↗
PubMed1986

[State of the microcirculation and its relation to gastric function and structural changes in the gastroduodenal zone in recurrent peptic ulcer].

A total of 108 patients with peptic ulcer were entered into the study. Examination of the microcirculation in the eye conjunctiva and microvessels of biopsy specimens of the mucous membrane taken from ulcerous areas revealed that disease relapses were marked by pronounced disorders of the end blood flow. The extent of the disorders was found to be determined by the activity and localization of the pathological process, structural alterations in the mucous membrane of the gastroduodenal area, and by gastric functions.

Adolescent↗
PubMed1985

[Histamine metabolism in patients with chronic gastritis].

Examination of 104 patients has demonstrated that in marked exacerbation of chronic gastritis, surface involvement of the gastric mucosa largely localized to the fundal part, high acid-peptic activity and short-term duration of the disease, absolute hyperhistaminemia are noted. Subsiding gastritis exacerbation, the presence of glands atrophy, primary involvement of the mucous membrane in the antral part of the stomach, secretory insufficiency, as well as the disease of many years are accompanied of absolute hypohistaminemia manifesting in a low blood histamine content, the activity of histaminase and histaminopexia being unchanged or elevated.

Adolescent↗