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Biomedical subjects

V V Delektorskij

Publications and source records attributed to V V Delektorskij.

13 recordsLinked to original sources
PubMed1976

Ultrastructure of gonococci in acute, chronic, and asymptomatic gonorrhoea.

The authors have made an electron microscope study of material from patients with acute, chronic, and asymptomatic gonorrhoea both before and during treatment with penicillin and kanamycin. Some features of the structure of the gonococcus, e.g. the six-layered cell wall, and of the reactions of the organism in different forms of gonorrhoeae before and during treatment with antibiotics were demonstrated using Ruthenium red staining. Thus, in chronic gonorrhoea, the presence of structures similar to gonococcal L-forms was found to be characteristic, while in asymptomatic gonorrhoea the formation was observed of multimembrane phagosomes hampering the penetration of drugs and antibodies. The positioning of gonococci round epithelial cells was noted (cellular energy). The possibility of changing treatment procedures is examined in the light of these observations.

Acute Disease↗
PubMed1975

Treponema pallidum in nerve fibres.

Ultrathin sections of a rabbit scrotal syphiloma were examined by electron microscopy. Treponemes were observed in the endo-, peri-, and epineurium of the nerve fibre. The significance of these findings, in that infection may be transmitted via the nerve fibres and pain reduced by damage to the afferent fibres, are discussed.

Animals↗
PubMed1975

Further studies of Trichomonas Vaginalis with transmission and scanning electron microscopy.

Under the scanning electron microscope, the body surface of trichomonads appears ruffled and creased, with numerous crater-like depressions, which should probably be interpreted as the initial stage in the formation of digestive vacuoles or pinocytotic vesicles. Having contacted epithelial cells, trichomonads engulf them totally or partially. Various micro-organisms also become a prey of the protozoon. The different stages of phagocytosis are illustrated in electron micrographs. Gonococci have been discovered in phagosomes of T. vaginalis. Usually their phagocytosis is not brought to completion and they survive within the trichomonads (endocytobiosis). This suggests that the agent of gonorrhoea may be maintained within trichomonads in cases of mixed infection. In addition to morphological details described earlier, T. vaginalis has lattice-like and lamellar structures of uncertain function. Spherical forms are found usually in an unfavourable environment or as a result of budding.

Cell Nucleus↗
PubMed1966

Morphology of Treponema pallidum.

In recent years many investigations have been carried out on the morphology of Treponema pallidum by means of the electron microscope, and the use of ultra-thin sections has shown up a number of structural details. However, there is still need for much more evidence before the internal structure of treponemes can be elucidated fully and the functions of the structures interpreted. To provide such evidence, the authors have examined under the electron microscope negative-stained treponemes and ultra-thin sections, using both cultivated strains and treponemes obtained direct from syphilids in people suffering from fresh secondary syphilis. It has been shown that treponemes have a complex structure. T. pallidum has a two-layered outer wall, a cytoplasmic membrane proper, cytoplasm and a bunch of fibrils following a different path in different places on the treponeme. The sites of insertion of the fibrils (the basal granules) were investigated; structures similar to mesosomes and nucleoids were found. Cysts and granular forms are described.

History of Medicine↗