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Biomedical subjects

V V Evstaf'ev

Publications and source records attributed to V V Evstaf'ev.

18 recordsLinked to original sources

Ultradian biorhythms of cell proliferation.

We studied circadian and ultradian rhythms of mitotic index of epithelial cells of the esophagus, intestine, and dorsal surface of the tongue, and thymocytes from mice maintained at normal and inverted light regimens. It was shown that in normal animals, the period of ultradian oscillations was shorter during the active circadian phase compared to the passive phase. Photoinversion changed the correlation between ultradian oscillations of the mitotic index and its circadian phases, which was differently pronounced in various tissues. Thus, changes in daily illumination serve as the time indicator for circadian rhythms of cell proliferation, but not for ultradian oscillations of mitotic activity.

Animals↗

[Dermatologic pathology in chronic alcoholics].

A total of 1159 chronic alcoholics, treated at narcology departments, have been screened for dermatologic diseases. The reference group consisted of 2735 subjects matched for age and working conditions, but not abusing alcohol. Skin diseases have been detected in 43% of alcoholic patients; this is almost 5 times more that in the reference group. Psoriasis has been found 10 times more frequently in these patients than in the controls. These results prompt that dermatologists should take part in comprehensive examinations and treatment of alcoholic patients.

Adult↗

[The use of a heparin ointment in combination with dimexide in treating psoriasis].

Thirty-five male patients with psoriasis en plaques, persisting for 2-5 years, resistant to routine therapy, were treated with official heparin ointment with 15% dimexide under an occlusion dressing. Positive results were achieved in 41.2 +/- 5.9 days of the ointment application. Complete resolution of the rash was observed in 19 (54.3%) patients, partial regression in 14 (40%), no effect in 2 (5.7%) patients. This ointment is recommended for active therapy of patients with local psoriatic plaques with a stable course of the condition, torpid to routine antipsoriatic therapy.

Adult↗