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Biomedical subjects

V V Ivanov

Publications and source records attributed to V V Ivanov.

At least 19 recordsLinked to original sources
PubMed1995

[GeneBee-NET: An Internet based server for biopolymer structure analysis].

A network server providing biopolymer structure databank retrieval as well as some other biocomputing procedures for Internet users is described. Its basic procedures consist in looking for sequence and 3D homologies (similarities). Found homologies are used for constructing multiple alignment, for predicting RNA and protein secondary structures as well as for constructing phylogenetic trees. Alongside traditional methods of sequence homology retrieval, a "matrix-free" (correlation) method is proposed. A similar procedure is used to locate protein 3D similarities. For novel procedures algorithm ideas and their possible applications are discussed. The service ideology is based on the interaction of server and client programs. The client program (GeneBee for IBM PC) can be used to form queries to the server as well as to manipulate a treatment result. In the absence of the client program the interaction with the server can be in the text mode. The E-mail and WWW addresses for the server are as follows: SERVE/INDY.GENEBEE.MSU.SU and WWW.GENEBEE.MSU.SU.

Amino Acid Sequence↗
PubMed1992

[Morphological evaluation of fetal development after administration of Poterium sanguisorba for correction of fetoplacental circulation].

Polyphenol preparation of Poterium sanguisorba was tried for the treatment of experimental pregnancy abnormalities. The teratogenic and embryotoxic effects of the preparation administered in a dose of 0.75 LD50 were studied. The therapeutic doses of the drug are characterized by an immunostimulating effect on the mother and help correct the fetoplacental circulation and improve the fetal morphofunctional status.

Animals↗
PubMed1991

Low-density lipoproteins interact with liposome-binding sites on the cell surface.

Under physiological conditions significant amounts of low-density lipoprotein LDL particles ar taken up by cells independently of specific high-affinity LDL receptors (apo-B receptors). Previously it was established that some cells contain surface sites capable of binding liposomes. We proposed that liposome-binding sites could contribute to LDL interaction with the cell surface via phospholipid molecules of LDL particles. To check this hypothesis we studied the competitive interaction of human LDL and DPPC liposomes with mouse embryo fibroblasts depleted of apo-B receptors by preliminary incubation with LDL. We have found that after removal of the liposome-binding sites from cell lamellae these areas of the cell surface lose their ability to bind LDL.

1,2-Dipalmitoylphosphatidylcholine↗
PubMed1991

[Characteristics of physiological reactions during work in coal miners with hypertension].

Vegetative equilibrium disorders in hypertensive-diseased miners resulted from pathologic developments in the limbic -reticular structures. Those were characterized by a hyperfunction of the ergotropic nerve formations. The vegetative control reorientations were accompanied by narrowing the amplitude of the homeostatic regulation vegetative reactions and engaging the mechanisms of adaptation. The vegetative state stabilization in the diseased workers was attained through a partial avoiding ot the most labour-intensive forms of activity and choosing more preferable labour operations. But the latter did not entirely exclude the labour conditions which would result into inadequate vegetative reactions.

Adult↗
PubMed1991

[Rheovasography in the evaluation of conservative treatment methods in obliterating atherosclerosis].

The work discusses the results of treatment of 65 patients for arteriosclerosis obliterans of the lower limb vessels by means of various nonoperative methods. The clinical indices improved within the shortest period of time in the group of patients treated by a complex of measures including reinfusion of blood irradiated by ultraviolet rays. According to the findings of rheovasography, the rheographic index increased to a greater degree (+0.4) in patients who were treated by infusion of their own blood, which had been exposed to ultraviolet light, in combination with intravenous injection of drugs. Application of quantum hemotherapy alone was also effective, which was confirmed by increase of the rheographic index by 0.2. It is pointed out that the therapeutic effect of the method is mainly due to improvement of the blood rheologic properties and provision for the flow of blood along the main channel.

Aged↗
PubMed1990

[Susceptibility to suggestion in patients with hysterical neuroses].

It is common knowledge that patients with hysteric neurosis demonstrate selective suggestibility in respect of different methods of suggestion, namely from high to extremely low. To specify the nature of such selectivity, a study was made of the dependence of hysteric neurosis patients' suggestibility on their personality and typological traits and the clinical manifestations of neurosis. It has been shown that suggestibility of patients suffering from hysteric neurosis depends on the premorbid (hysteroid, excitable and inhibitory) types of the patients' personality and the clinical picture of neurosis. It has been also discovered that patients belonging to the premorbid hysteroid type are most suggestible whereas those belonging to the premorbid inhibitory type are least suggestible.

Adolescent↗
PubMed1990

[Changes in lymphocyte size after chronic exposure to radiation and chemical factors].

Results of the analysis of changes in peripheral blood lymphocytes size under chronic exposure to external gamma radiation and pesticide chlorophos++ in combination and separately are presented. It has been found out that under exposure of animals to radiation or the pesticide it is small and big lymphocytes respectively which most significantly suffer quantitatively. Under the joint radiation ++-chemical exposure of the organism the number of both types of cells is reduced simultaneously.

Animals↗
PubMed1990

[Use of laser irradiation in the complex ambulatory treatment of arthrosoarthritis].

The article discusses experience with the treatment of 60 patients with arthrosoarthritis deformans of various large joints by the traditional conservative methods and with the use of laser radiation by an Uzor biomedical laser device. The authors noted a positive effect of laser radiation on the pathological processes developing in the region of the involved joint, which reduced the terms of treatment from 24.4 to 10.4 days and considerably reduced the number of recurrences in the immediate period.

Adult↗
PubMed1989

[Surgical treatment of myasthenia gravis in children].

The article deals with the treatment of myasthenia in 33 children whose ages ranged from 3 to 15 years. Myasthenia of moderate severity was diagnosed in 14, severe in 15, and extremely severe in 2 children. To make a precise diagnosis, loading, neostigmine methylsulfate, cold, and D-tubocurarine tests were conducted. Thymectomy was performed in 32 patients. The operation was carried out through a T-shaped sternotomy approach. Thymogenic myasthenia was verified in 31 patients and thymomogenic only in one patient. There were no fatal outcomes. The late-term results were studied in 12 patients in follow-up periods of 3 to 6 years. Adaptational activity of the patients, anticholinesterase agents and the results of stimulant electric myography served as the criterion in appraising the late-term results. Modern diagnostic methods and surgical intervention ensure a favourable result in 75% of patients.

Adolescent↗
PubMed1989

[The development of a questionnaire scale for determining individual hypnotizability].

Based on the MMPI test the authors developed a scale-questionnaire for predicting the degree of individual hypnotizability before realization of hypnotherapy. Forty-two assertions were singled out, affirmative answers to which make it possible to determine the probable hypnotizability of the subject according to a special scale comparable with the Katkov scale for assessment of the "depth" of the hypnotic state.

Adolescent↗
PubMed1989

[Dependence of the levels of morbidity with temporary loss of work capacity on the body functional state of those working in hypokinesia].

The study was designed to analyze the relation of body functioning and temporary disability rates in order to identify physiologic indices characterizing health status and its possible variations. As illustrated by the data on health status of female workers engaged in precision assembly work and exposed to hypokinesia it was established that the indices of general physical work capacity could be used for predicting possible changes in workers' health state. The workers with high levels of physical capacity for work had lower morbidity rates, that tendency being especially revealed in workers of older age groups.

Absenteeism↗
PubMed1989

[Effect of low-molecular toxic substances on the organs of the immune system in mothers and their offspring].

Administration of benzpirene to the mother is accompanied with activation of B-and decrease in T-links of immune activity both in the mother and offspring. The lymphoid organs in the animals, not subjected antenatally to benziprene action, but given the substance after birth, undergo destabilization and are not ready to administration of this polycyclic hydrocarbonic compound. This produces their hypoplasia. It is quite possible, that under this condition the activity of the cellular link of immunity decreases, and the humoral one is stimulated. Certain morphofunctional connections are supposed to exist between the immune systems of the mother and the fetus. The antenatal action of benzpirene causes a responsive reaction in the offspring as an immunological commemoration, and it ensures the level of the immune response.

Animals↗