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This paper describes a method for simulating transient endolymphatic hydrops based on the generation of vasomotor disorders in the labyrinthine artery area. The method is based on a deep short-term chloroethyl freezing of the lateral surface of the animal surface in the projection of the spinal artery. In histological terms, hydrops is characterized by two factors: vascular lesions (hyperemia of the vascular stripe, venous congestion) and changes in physico-chemical parameters of labyrinthine fluids (edema of cell elements of the labyrinth, membrane deformation, precipitation of the granular-reticular residue in the endo- and perilymphatic spaces). This method can be used to study the origin of endolymphatic hydrops during Ménière's disease, to develop new approaches and to give a pathogenetic substantiation of existing approaches to the treatment of Ménière's disease.