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Biomedical subjects

V V Kislukhin

Publications and source records attributed to V V Kislukhin.

15 recordsLinked to original sources
PubMed1990

[Possibilities of the method of dilution of electro-impedance indicators in the assessment of volume dynamics of extravascular lung fluid in intensive care and resuscitation units].

The possibility of using impedance plethysmography to assess changes in the volume of the extravascular lung fluid in intensive therapy and resuscitation patients is discussed. Changes in the volume of the fluid during extracorporeal detoxication are analysed. A correlation was found between these changes and lung distensibility (r = -0.7). A significant diminution of the fluid volume was observed in response to therapeutic doses of Lasix and Nitroglycerin. Data are cited on the increasing (85 percent) volumes of the fluid in preclinical pulmonary edema in patients with left ventricular insufficiency.

Body Fluids↗
PubMed1989

[Study of parameters of central hemodynamics in patients during hemodialysis].

The article discusses the results of study of the cardiac output (CO) and circulation blood volume (CBV) in patients at the beginning and end of hemodialysis. The dynamics of changes of these parameters during hemodialysis was studied in 31 patients (42 sessions). The CO and CBV reduced significantly. In a group of 10 patients who felt worse, the CO reduced by more than 30 per cent in 7, the CBV diminished by 25 and 30 per cent in 2, and CBV and CO reduced by more than 30 per cent in 1 patient in relation to the initial level. The CO and CBV were measured by means of the method of dilution of electroimpedance indicators.

Blood Volume↗
PubMedDate not supplied

[The electrical impedance indicator dilution method in studying the basic hemodynamic parameters during dialysis].

The procedure for measuring cardiac output and circulating blood volume is based on blood ability to modify its electrical conductance due to the amount of introduced ions (0.9% sodium chloride solution) or undissociated molecules (5% glucose solution). The cardiac output and circulating blood volume were calculated after measuring an area under the electrical impedance indicator dilution curve using the given formulas. With the described and thermodilution methods, the cardiac output was compared (r = 0.95). The correlation factor with the radioisotopic method in measuring the circulating blood volume was 0.88. Clinical investigations carried out in 47 patients on a programmed hemodialysis showed a significant decrease in cardiac output approximately by 700 ml/mi (7.9%) and circulating blood volume by an average of 900 ml (15.2%) by the end of a hemodialysis session, the rate of the circulating blood volume to body weight being also decreased. There was a predominant fluid "release" from the vascular bed.

Blood Volume↗
PubMedDate not supplied

[The use of a vitamin and metabolite complex for correcting the disorders in systemic and organ hemodynamics during liver resection under conditions of acute blood loss].

The efficacy of some infusion media, vitamins, and metabolites in resection of the liver in acute blood loss was studied in experiments on dogs. Inclusion of vitamins B1, B2, and B6, lipoic acid, calcium pantothenate, nicotinamide, solution of alpha-glutamate and gamma-aminobutyric acid (aminalone) in the infusion led to a sharp increase of myocardial contractility, increase of cardiac output and total hepatic blood flow, normalization of biochemical blood values, and restoration of the activity of hepatocyte enzymes.

Acute Disease↗
PubMedDate not supplied

[Determination of hemodynamic parameters by blood electrical resistance using a dilution method].

The theoretical basis and the experimental data of the hemodynamic parameter determination method have been described. The cardiac output and the circulating blood volume have been determined using intravenous injections of two solutions with different electrical resistance. A formula for blood electrical resistance was proposed. Tolerances for isoosmotic solutions were made. A system of three equations was made up on the basis of the results of two injections of solutions with different electrical conductance. From these equations blood characteristics, cardiac and circulating blood volumes can be obtained. Isoosmotic solutions of glucose and sodium chloride were used as indicators in treadmill tests with circulating blood. The measurement error practically didn't depend on the electrode type (either along or across the flow).

Blood Physiological Phenomena↗
PubMedDate not supplied

[Determination of the volume of extravascular fluid in the lungs by blood electrical resistance using a dilution method].

The theoretical basis of the method determining the volume of the extravascular lung fluid has been considered. The fluid volume is found by measuring the volume of water passing from the lung into the blood through the hyperosmotic indicator. The water volume is determined by comparing the curves of electrical resistance obtained as a result of intravenous injections of isoosmotic and hyperosmotic solutions. The electrical resistance of the blood is measured in the arterial bed. The lung fluid volume can be calculated using the parameters of the dilution curves and the equation for the crossing point.

Blood Physiological Phenomena↗
PubMedDate not supplied

[Dynamics of the content of the pulmonary extravascular fluid during extracorporeal detoxication in critical state patients].

Time course of the content of interstitial, cellular, and total fluid in the lungs, of plasma osmolality and sodium concentration was studied in 20 patients with acute renal failure after repair surgery on the heart, thoracic and abdominal organs. Water balance of the lungs was studied by dissolution of electroimpedance indicators before and after removal of 2000-2500 ml of ultrafiltrate. Ultrafiltration of the blood in the course of hemodialysis (group 1) did not lead to a reliable reduction of the volume of intravascular fluid, whereas in group 2 a reliable reduction of the volume of interstitial fluid of the lungs by 34% and of the total liquid volume of the lungs by 29% occurred in the course of hemofiltration.

Acute Kidney Injury↗