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Biomedical subjects

V V Laptev

Publications and source records attributed to V V Laptev.

At least 19 recordsLinked to original sources
PubMed1994

[Basic principles of treatment for patients with acute pancreatitis].

The results of treatment of 1,320 patients with acute pancreatitis were analysed, 460 of them had the destructive form of the disease. The high significance of multicomponent etiopathogenetic treatment is demonstrated. The importance of etiotropic treatment with the application of endoscopic interventions, as well as treatment with cytostatics is emphasized. Timely combined use of these methods prevents a progressive uncontrolled course, and reduces the volume of treatment and its duration. The authors also discuss the first experience in nontraditional management of patients with postnecrotic cavitary complications of pancreonecrosis by the aspiration "closed" method with the use of ultrasound.

Acute Disease↗
PubMed1987

[Immunoregulation in the treatment of patients with acute pancreatitis].

The article analyses certain indicators of immune reactivity in 67 patients with different forms of pancreatitis. Lower reactivity of the organism in destructive pancreatitis determines the necessary use of immune modulating therapy in the complex treatment of this disease and purulent complications. In patients with high risk of pyo-septic complications the administration of cytostatics is not indicated.

Acute Disease↗
PubMed1986

[Morphology of the pancreas during intra-aortal administration of 5-fluorouracil].

The results of the studies of morphological changes in the pancreas during intraaortal injections of various 5-fluorouracil doses to 44 dogs are reported. It was experimentally established that intraaortal injection of 10 mg 5-fluorouracil per kg of mass for 3 days caused the delay in albumin-synthesizing organella function, without damaging organellas as such. Administration of a cytostatic in a dose of 15 mg per kg of mass did not only cause a drastic decline in the synthesizing activity of cells in acinar parenchyma, but also induced intracellular lesions.

Animals↗