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Biomedical subjects

V V Malyshev

Publications and source records attributed to V V Malyshev.

5 recordsLinked to original sources

[Modification of the cellular and vascular reactions in the inflammatory focus by luteotropic hormone].

Luteotropic hormone considerably alters the dynamics of experimental inflammation. A decrease of microvascular bed activation and the density of macrophage population are observed at early stages of the inflammation. Inhibition of fibroblast proliferative activity and acceleration of their differentiation are revealed during the period of reparation. The formation of the capsule went more intensely, but collagen synthesis was inhibited and fibrous tissue formed more slowly. The results obtained prove principal possibility of inflammation regulation by means of mediators and metabolites of the stress-limiting systems.

Animals

[The etiological structure and epidemiological characteristics of viral hepatitis among servicemen].

Selected studies on etiological structure of hepatitis A were conducted among servicemen, using modern high-sensitive orrhological methods of diagnosis. 325 serums obtained from infectious patients were examined in the laboratory. On the basis of this analysis the authors make a conclusion concerning a rather high level of fecal-oral viral hepatitis among servicemen of the 40th Army, which differed from hepatitis A.

Afghanistan

[Effect of craniocerebral hypothermic perfusion on the metabolism of ischemic brain].

Intravascular perfusion of the brain by colloid-saline "extracellular" fluid was carried out in 58 experimental dogs against the background of acute hypoxia. Biochemical indices of metabolism in flowing and outflowing brain fluid as well as in the brain tissue were studied. It was shown that under conditions of acute hypoxia normo- and particularly hypothermic intravascular perfusion of the brain by colloid-saline fluid decreases the disturbances of metabolic homeostasis.

Animals

[Decrease in the stress reaction and the ulcerative lesions of the stomach under the influence of gamma-hydroxybutyric acid].

The effect of preliminary Na gamma-hydroxybutyric acid (GHBA) injection on the activation of adrenergic and hypophyseal-adrenal systems during emotional-painful stress and ulcerous affection of the stomach after the stress cessation was studied in experiments on rats. It was established that the preliminary GHBA administration inhibits stimulation of stress causing systems and thereby prevents ulcerous affection of the stomach mucosa. It is suggested that the activation of GHBA-ergic inhibiting system, which accompanies the stress, is a natural mechanism of limitation of the stress reaction and prevention of the stress affections.

Animals

[Changes in the content of eosinophils, corticosterone and catecholamines during liver regeneration following resection].

Experiments on albino rats demonstrated changes in the-blood eosinophil level, as well as in the content of catecholamines and corticosterone in the plasma, the adrenal glands, and the heart following partial hepatectomy. Phasic character of the hypophysis-adrenal system responses to resection and the processes of the liver regeneration was revealed, and this is reflected in the eosinophil level.

Adrenal Glands