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Biomedical subjects

V V Shcherbakov

Publications and source records attributed to V V Shcherbakov.

9 recordsLinked to original sources
PubMed1980

[Lymphoid tissue of the human vermiform appendix and its cellular composition at different ages].

The lymphoid tissue of 55 human appendices has been studied beginning from 25 weeks of the intrauterine development up to 80 years of age. Most of lymphocytes have been found to include immunoglobulines of various types; in some cases alcaline phosphatase activity was evident in lymphocytes of the mantle zone of lymphatic follicles in children and grown-up persons, and lack of acidic phosphatase activity in lymphocytes make it possible to consider the appendicular lymphoid tissue as a B-dependent type of lymphoid tissue. A suggestion is made that during the intrauterine development and the early childhood the appendicular lymphocytes could settle in other lymphoid formations.

Acid Phosphatase↗
PubMedDate not supplied

[Problems in organization of medical criminological registration and personality identification for subjects occupationally exposed to life risk].

The paper discusses problems in organization of identification studies under conditions of mass deaths as exemplified by forensic medical records of medical criminological identification studies of subjects killed during war conflict in Chechnya. The evolution of the organization model of identification studies is shown transformation of organization philosophy, formation of expert algorithms, formalization and technologic realization of expert solutions.

Criminology↗
PubMedDate not supplied

[Use of computer software for indirect molecular genetic identification of unidentified bodies].

The authors discuss the development and use of computer software for realization of indirect DNA identification, based on identification of biological relation. Estimated algorithms of this method are based on regularities of parental signs inheritance by children and consist in comparative analysis of allele states of nuclear DNA typed locuses in unidentified bodies and probable parents of these dead subjects and subsequent estimation of the coefficients of the likelihood of hypotheses of their probable blood relationship. Available software maintain the database with identification characteristics of VNTR and STR locuses, HLA DQA1 locuses, and PM system (potential set of 23 locuses). The results of identification are presented as lists of exclusions and tables with estimated likelihood coefficients for the probability expert evaluation of relationship. The suggested computer-aided method of indirect identification is a new highly effective tool for personality identification by chromosome markers under conditions of mass information processing in examinations of unidentified corpses.

Algorithms↗
PubMedDate not supplied

[Design of the automatic system of processing data on mitochondrial DNA "mDNAbase" sequestration for expert identification of the unidentified bodies under the conditions of mass reception of human remains].

The authors consider utilization of software which provides indirect personality identification by establishment of biological kinship using a comparative analysis of nucleotide sequences (NS) of mitochondrial DNA (mtDNA) in unidentified bodies and suspected relatives of these victims. The software supports data bases with information on NS. To secure automatic search there are modes of cross-processing. Results of identification are formed as lists of exclusions and tables with calculated frequencies of mitotypes of identification objects as well as protocols of a comparative analysis of nucleotide position in mtDNA sequences under comparison. The proposed computer approach is a new highly effective tool for identification of personality based on data on mtDNA analysis in conditions of stream information processing under mass reception of unidentified bodies.

Cadaver↗
PubMedDate not supplied

[An algorithm of computerized processing of molecular-genetic data for personality identification based on the outcome of events involving numerous victims].

Computerized systems of data processing are a high-efficiency tool for the storage and processing of big volumes of molecular genetic data as well as for the forensic medical identification of personality in events involving enormous unidentified bodies coming from zones of calamity or natural disaster. Described in the paper is a sequence of actions undertaken by the expert when the DNAdacto and mDNAbase soft tools are in use. The algorithm of computer-based expert analysis of typing of chromosome and mitochondrial DNA was tested at the 124th Central laboratory of medical-criminal identification of Russia's defense ministry; it was proven to be highly effective for identification made in events with numerous unidentified bodies.

Algorithms↗