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Biomedical subjects

V V Speranskiĭ

Publications and source records attributed to V V Speranskiĭ.

At least 19 recordsLinked to original sources
PubMed2006

[Hair trace elements in patients with goiter].

The investigation determined whether there was a relationship of thyroid diseases with the geology of the place of residence and its associated spectrum of trace elements (iron, chromium, selenium, manganese, cobalt, copper, nickel, arsenic, and zinc). The geologo-geomorphological factors of the habitat, such as geological formations (mineral composition, structure, the degree of rock metamorphism), tectonics, the history of geological development, relief, paleorelief, were found to be of considerable importance in the formation of the human trace element status. Both deficiency and excess of trace elements was shown to be of pathogenetic value in the development of thyroid diseases. Residence in the area wherein carbonate rocks are predominant contributes to an increase in incidence of thyroid diseases.

Ecosystem↗
PubMed1999

[The effect of the essential fatty acids in mare's milk on the function of the immune system and of nonspecific resistance in rats].

The influence of essential fatty acids of mare's milk fat on the immunocompetent system and nonspecific resistance of male rats weighing 135-145 g was investigated after 6 weeks of feeding. Rats were fed with isocaloric purified diets containing 15% of test fat (in control--combination of lard and sunflower oil) which provide the ratio of omega-6/omega-3 fatty acids equal to 0.76. An increase of immune responsiveness and nonspecific resistance in the group fed with the diet with mare's milk fat on day 6 after a single immunization of the animals with 5% sheep erythrocyte suspension was noted.

Animals↗
PubMed1989

[Effect of immunologic shifts on the results of the surgical treatment of hyperthyroid goiter in children].

The authors discuss the effect of immunological shifts in 102 children with hyperthyroidism goiter on the outcomes of surgical treatment. Deviations in the immune status of children suffering from this disease were found to have an unfavourable effect on the outcome of surgical treatment. Recurrences were more frequent and postoperative hypothyroidism developed. The initial condition of the immune status helps in prognosing the further course of the pathological process and guides the therapeutic correction in the pre- and postoperative periods.

Adolescent↗
PubMedDate not supplied

[Immunological status and its changes in children during surgery on anterior eye segment].

Nonspecific and specific immunity values were studied in 70 children before and in various periods after 74 operations on the anterior segment of the eyeball. In children with persistent autosensitization to ocular tissue autoantigens (alpha-crystalline and S-antigen) postoperative uveitis presented as an immunocomplex disease with signs of exhaustion of the functional potential of the phagocytosis and complement systems. In children without autosensitization uveitis was associated with immunity activation. Phagocytosis system and cooperation of lymphocyte subpopulations, including normal killers (CD16+), play an important role in prevention of sensitization to ocular tissue autoantigens. Therefore, complex immunological examinations of children before surgery and regular check-ups after it will help differentiate immunodeficiency from compensatory immunosuppression preventing autoimmune disease, which is important in prescription of immunostimulating therapy.

Adolescent↗
PubMedDate not supplied

[Early diagnostics of hemorrhagic fever with renal syndrome on the basis of the use of Pumala virus recombinant nucleocapsid protein].

Pumala virus recombinant nucleocapsid protein was used for the early diagnosis of haemorrhagic fever with renal syndrome. Specific IgM in the sera of patients could be determined by the IEA technique as early as on days 2-3 from the onset of the disease. The diagnostic effectiveness of the test-system was 95% and its specificity was 98%.

Antibodies, Viral↗
PubMedDate not supplied

[Regulation of the blood-brain barrier permeability in suppurative-inflammatory diseases of the maxillofacial area].

Hematoencephalic barrier (HEB) permeability was studied in 78 rabbits. HEB permeability for 32P was examined in animals with phlegmons on the posterior paws and on the maxillofacial area; HEB permeability was sharply increased in the latter group animals. Central cholinolytics and antioxidants were used to normalize this parameter in the rabbits with maxillofacial phlegmons.

Animals↗