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Biomedical subjects

V V Stepanenko

Publications and source records attributed to V V Stepanenko.

14 recordsLinked to original sources
PubMed2001

[Functional state of monocytes and some of their regulatory mechanisms during development of stress reactions].

In model researches on laboratory animals, reproducing experimental selective mielodepresion, is established, that at a realization in an organism of a unspecific stress-syndrome, in an outcome immobilization, in circulating neutrofiles the jet changes lysosomal of the vehicle determining increase in whey of activity some them lysosomal enzymes happen, that immediately can render influence to a series of parameters of functional activity monocytes of blood.

Agranulocytosis↗
PubMed1998

[The effect of insulin on the function of the lysosomal apparatus of the neutrophilic leukocytes during the formation of a stress syndrome].

In experiments on male rabbits with the lack of insulin it is been revealed violations after the past immobilization the intensivity and duration of neutrophilic leukocytosis decrease, contents of lysosomes in neutrophils, activity of acid phosphatase. By lysosomal ferments don't determine the can observer discordance of processes of coagulation, fibrinolysis, kininogenesis.

Acid Phosphatase↗
PubMed1990

[An analysis of the dysentery epidemic process in Blagoveshchensk].

The retrospective analysis of dysentery morbidity in Blagoveshchensk for the period of 1960-1987 was made. The regularities linking general natural and biological factors triggering the epidemic process with dysentery morbidity among the population are emphasized. The study revealed that under the conditions of Blagoveshchensk dairy products were of major epidemic importance among factors contributing to the transmission of dysentery. Such a factor as flies also had a definite influence on the epidemic process of dysentery. Another risk factor was drinking water which influenced the epidemic process both directly and indirectly through dairy products and, probably, other foodstuffs. Reliable correlation between dysentery morbidity among the population and the quality of dairy products, tap water and the number of flies was established.

Animals↗
PubMedDate not supplied

[Bile secretion in dogs after intravenous administration of glucose].

The effect of drop infusions of 10% glucose solution for parenteral nutrition, in a dose of 2 g/kg, on bile secretion was studied in experiments on dogs with chronic gallbladder-duodenal fistulas. It was demonstrated that the infusion of hypertonic glucose solution inhibits bile production quantitatively and qualitatively.

Animals↗
PubMedDate not supplied

[Experimental study of the effect of intravenous administration of sorbitol on bile excretion].

Experiments were made on dogs with chronic U-shaped gall bladder-duodenal fistulas. The animals received 10% sorbitol (0.6 g/kg) injections into the peripheral vein. Analysis of total bile acids cholesterol and total bilirubin in hourly portions of the bile showed that sorbitol known to produce a choleretic effect when administered enterally and intraduodenally failed to have a choleretic effect after intravenous injection.

Administration, Oral↗
PubMedDate not supplied

[Antitoxic action of cobamamide in experimental hepatitis].

Antitoxic properties of cobamamide, a coenzymic form of vitamin B12, were studied in experimental toxic hepatitis induced by CCl4. The data obtained as a result of the assessment of the bromosulfalene test and activity of sorbitol dehydrogenase and alanine aminotransferase point to a demonstrable hepatoprotective action of cobamamide. Normalization of the indicators studied evidences that the drug intensifies the recovery processes occurring in the liver of rabbits with toxic hepatitis.

Alanine Transaminase↗