PubMed Health⌕ Search

Biomedical subjects

V V Surovikina

Publications and source records attributed to V V Surovikina.

2 recordsLinked to original sources

Enterosorption in oncotherapy.

Patients with lymphogranulomatosis undergoing radiotherapy according to the radical scheme were treated with fibrous carbon enterosorbent VESTA in tablets for 14 days (group I, 23 patients) from the moment of leukopenia development (lower then 2.2 x 10(9)/l) or were traditionally treated using parenteral administration of hemostimulants, hemosubstitutes and detoxicants (group II, 23 patients). After 14 days leukopenia was cured in 18 patients of group I (78%) and in 11 patients of group II (48%), with an average number of leukocytes in the patients of groups I and II growing by 2 and 1.6 times, respectively. The administration of enterosorbents enabled interruptions in radiotherapy caused by the development of leukopenia and the deterioration of health status to be greatly shortened and the requirements in expensive transfusion media to be sharply reduced.

Adult↗

[The distribution of HLA-system antigens in lung cancer patients].

Data on 152 cases of lung cancer were studied in an attempt to identify relationship between immunogenetic markers of the HLA system, on the one hand, and histologic pattern of the disease and effectiveness of radiation treatment, on the other. Control group included 200 healthy blood donors. Eight A locus antigens and 16 B locus antigens were studied. In the entire group of patients, HLA-Aw19 antigen was observed less frequently as compared to controls. Similarly infrequent were haplotypes containing the antigen. The occurrence of HLA-B16 antigen was higher in the adenocarcinoma group. Resistance to treatment, particularly, in patients with small-cell histology was associated with the presence of HLA-B8 antigen. Possibility of tissue typing of antigens for diagnosis and prediction of response in lung cancer patients is discussed.

Adenocarcinoma↗