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Biomedical subjects

V V Usachev

Publications and source records attributed to V V Usachev.

12 recordsLinked to original sources
PubMedDate not supplied

[Therapy of primary open-angle glaucoma by oftan-dipivefrin].

Choice of optimal hypotensive therapy with the minimal side effects remains a serious problem in therapy of glaucoma. The efficacy and safety of oftan-dipivefrin (Sante, Finland) and glaucon (Alcon, USA) are compared in a controlled balanced randomized open parallel study preceded by a period for discharge of the previous drugs. The period of discharge was 7 days, active treatment was administered for 8 weeks. Sixty patients aged 61-69 years were treated. Thirty-one patients were treated by oftan-dipivefrin (group 1) and 29 by glaucon (group 2). In parallel with this, a 1% pilocarpin solution was administered in both groups. The examinations carried out during all consultations included measurements of intraocular pressure before instillations every day at the same time, evaluation of visual acuity, tonography, and study of the central and peripheral visual fields. The time course of hypotensive effects of both drugs showed a sufficient decrease in intraocular pressure in both groups; the effect of oftan-dipivefrin was more pronounced, while glaucon caused the least number of side effects.

Adrenergic Agonists↗
PubMedDate not supplied

[Human reactions to prolonged centripetal accelerations (+Gz) of small magnitudes].

The effect of centripetal acceleration (+Gz) of low values (0.5-0.6 g) applied for four days against the background of relative hypokinesia was investigated. The peripheral and intracranial circulations, equilibrium function and morphological composition of the capillary blood were examined. During the first three centrifugation days the hemodynamic state differed insignificantly from the initial level. On the fourth day signs of cardiovascular deconditioning were found. This was shown by the orthostatic test. Changes in the peripheral blood indicated a moderate stress-reaction that persisted throughout the entire experiment. Equilibrium changes that were observed on the first centrifugation day regressed and the post-test function did not essentially differ from the initial level. The experimental results give evidence that inertia forces can be used to diminish the unfavorable effects of hypokinesia.

Acceleration↗