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Biomedical subjects

V Vasile

Publications and source records attributed to V Vasile.

At least 19 recordsLinked to original sources

Trypsin treatment which elicits DNA synthesis, removes a high molecular weight glycoprotein from the plasma membrane of sea urchin embryonic cells.

SDS-polyacrylamide gel electrophoresis of plasma membrane proteins from sea urchin embryos at the swimming blastula stage allows the identification of fifteen-seventeen components, five of which are glycoproteins. One of these (molecular weight about 145,000) is almost completely absent in the plasma membrane of trypsin treated cells.

Animals

[The diagnosis and treatment of benign tumors of the subdiaphragmatic digestive tract].

One hundred twenty-two benign tumors of subdiaphragmatic digestive tract admitted in the interval 1975-1988 at the III-rd Surgical Clinic of Iaşi are reported. Out of these patients 120 required surgical treatment, the remainder of 2 being treated conservatively (diffuse intestinal angiomatosis, Peutz-Jeghers' syndrome). The clinical evolution being atypical, the surgical intervention was required, in most of the cases, due to hemorrhagic and occlusive complications. Histologically, the polyps and schwannomas were prevalent. The diagnostic difficulties, especially in the cases with jejuno-ileal localization, are mentioned.

Diaphragm

[The clinical, diagnostic and therapeutic characteristics in antral gastric cancer].

This paper is part of a comprehensive study on subphrenic digestive cancer carried out between 1984 and 1988, representing the experience of the III-rd, I-st, IV-th and emergency surgical clinics of Iaşi (1530 cases). The peculiarities of gastric cancer with antral site in 231 out of a total of 612 cases, representing the experience of the III-rd Surgical Clinic, are presented. Clinically, the relative early occurrence of the symptoms, the need for an endoscopic examination and biopsy for all gastric ulcer lesions, for the antral ones particularly, are mentioned. The treatment is surgical, but it has to be associated with adjuvant therapy. For the antral site, the oncological subtotal gastrectomy was the surgery of choice (157 cases), the need of restoring the transit in a gastrojejunal manner being underlined. Total gastrectomy was performed in 12 cases.

Combined Modality Therapy

[Antireflux surgery in the treatment of peptic esophagitis].

This paper deals with the outcome of the various "antireflux" surgical procedures performed in 21 patients having esophagitis. Immediate and long-lasting results are better for those methods which restore the gastroesophageal competence: Hill's operation (4) and Nissen's fundoplication (3). The participation of the stomach in producing reflux is stressed and is emphasized the necessity to treat the gastric lesions simultaneously. The duodenal diversion following Harrington procedure offers good results with minimal surgical risk in some particular cases.

Adult