Biomedical subjects

V Vitulová

Publications and source records attributed to V Vitulová.

At least 19 recordsLinked to original sources

PubMed1993

[Arthropathy and para-arthropathy in uremic patients on regular hemodialysis].

Arthropathies and para-arthropathies occur in two thirds of regularly haemodialyzed uraemic subjects. The incidence does not depend on age but the period of haemodialyzation treatment. After five years of treatment the articular apparatus is affected in 100%. In women, as compared with men, the joints of the upper extremities, in particular the small joints of the hands are significantly more frequently affected.

Adult↗

PubMed1989

[Prognosis in joint inflammation after acute respiratory diseases].

A group of 25 patients with arthritis after acute respiratory disease (ARD) was followed up, on average for 4.7 years, with regard to the short-term and long-term prognosis. The patients developed arthritis 1-4 weeks after ARD and it affected mainly or exclusively the joints of the lower extremities, in particular the talocrural ones. After a mean period of five weeks the arthritis receded completely. 60% of the patients were HLA B27+, the number of affected joints in these patients was greater than in HLA B27- patients. HLA B27+ subjects are more likely to develop arthritis after ARD than HLA B27- subjects (relative risk = 6.35). In the long-term prognosis articular changes were found in 6/22 patients (5 were HLA B27+): three times sacroileitis was found, twice a relapse of arthritis after repeated ARD and once systemic lupus erythematosus. As to laboratory tests, arthritis after ARD was associated with a transient response of reactants of the acute phase and serum IgG. High values of IgA and immunocomplexes, on the other hand, persisted throughout the investigation in 41% and 28% of the patients resp.

Acute Disease↗

PubMed1989

[Long-term observation of patients with isolated seropositivity for rheumatoid factor in the serum--clinical and immuno-rheumatological study].

A group of 40 subjects (33 women and 7 men) assembled in the course of several years comprised clinical and ambulatory patients. The main characteristic of the group was isolated seropositivity of rheumatoid factors assessed by the latex fixation test with titres of 1:320 and more in apparently healthy subjects. The mean age of the subjects at the beginning of the investigation was 39 years. They were followed up for 2-18 years, on average for 7.8 years. Regular clinical, biochemical and immunological check-up examinations were made after 1-2 year intervals. The latex fixation test was made in a test tube. The most serious manifestation was the development of rheumatoid arthritis in 7 subjects (6 women and 1 man). In two of them it was preceded by palindromic rheumatism. Two women have abortive manifestations of systemic lupus erythematosus. Seven developed, mostly repeatedly, tendovaginitis in the region of the flexors of the fingers and abductors of the thumb. Seven subjects suffered from polyarthritis of the hands. None of the subjects suffered from cirrhosis or monoclonal gammapathy. In the course of the investigation the titres of rheumatoid factors had a declining trend even to negative values. In 23 they became negative or had titres of 1:40. The high incidence of rheumatoid arthritis in 17% apparently healthy subjects with isolated seropositivity of rheumatoid factors emphasizes the importance of dispensarization of these subjects in a rheumatological surgery and of careful long-term follow up. Early administration of line 2 antirheumatic drugs could prevent a possible fatal course of rheumatoid arthritis.

Adult↗

PubMed1986