[Differentiation and verification of different forms of cardiogenic shock in acute myocardial infarct].
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Biomedical subjects
Publications and source records attributed to V Z Netiazhenko.
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Clinical pattern and complications of the disease were studied in 62 heparin-treated patients with large-focal myocardial infarction as compared to a control group of 59 patients treated with a polarizing mixture of glucose, insulin, potassium, analgetics and tranquilizers. The changes of the necrotic area and lesion were assessed on the basis of precardiac charting. The results obtained were correlated to the data on central hemodynamics, heart contractility and pumping function, gaseous exchange and acid-base balance. Heparin-treated patients showed a smaller rate of fatal outcomes, although primary ventricular fibrillation and heart failure prevailed in the mortality pattern in both groups. Heparin treatment improved central hemodynamics, contractility and pumping function of the heart, and gaseous exchange, while prestress decreased simultaneously, which is the optimum effect for patients with acute myocardial infarction. Precardiac charting data showed heparin treatment to be associated with a more rapid reduction in the depth of the ischemic lesion. The advantages of continuous intravenous heparin infusion are demonstrated.
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In 20 patients with acute myocardial infarction the parameters of coagulation and fibrinolysis were evaluated. A high degree of the correlation between the routine and turbidimetric methods was found. Turbidimetric express-micromethod may be widely used for monitoring coagulation and fibrinolysis parameters in patients with acute myocardial infarction.